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Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression.
Townsend L, Dyer AH, Naughton A, Imangaliyev S, Dunne J, Kiersey R, Holden D, Mooney A, Leavy D, Ridge K, Sugrue J, Aldoseri M, Kelliher JH, Hennessy M, Byrne D, Browne P, Bacon CL, Doyle C, O'Riordan R, McLaughlin AM, Bannan C, Martin-Loeches I, White A, McLoughlin RM, Bergin C, Bourke NM, O'Farrelly C, Conlon N, Cheallaigh CN; STAR COVID Bioresource. Townsend L, et al. Heliyon. 2022 Apr;8(4):e09230. doi: 10.1016/j.heliyon.2022.e09230. Epub 2022 Apr 1. Heliyon. 2022. PMID: 35386227 Free PMC article.
A novel anti-viral role for STAT3 in IFN-α signalling responses.
Mahony R, Gargan S, Roberts KL, Bourke N, Keating SE, Bowie AG, O'Farrelly C, Stevenson NJ. Mahony R, et al. Cell Mol Life Sci. 2017 May;74(9):1755-1764. doi: 10.1007/s00018-016-2435-3. Epub 2016 Dec 17. Cell Mol Life Sci. 2017. PMID: 27988795 Free PMC article.
Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection.
Townsend L, Dyer AH, Jones K, Dunne J, Mooney A, Gaffney F, O'Connor L, Leavy D, O'Brien K, Dowds J, Sugrue JA, Hopkins D, Martin-Loeches I, Ni Cheallaigh C, Nadarajan P, McLaughlin AM, Bourke NM, Bergin C, O'Farrelly C, Bannan C, Conlon N. Townsend L, et al. PLoS One. 2020 Nov 9;15(11):e0240784. doi: 10.1371/journal.pone.0240784. eCollection 2020. PLoS One. 2020. PMID: 33166287 Free PMC article.
Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity.
Townsend L, Dowds J, O'Brien K, Sheill G, Dyer AH, O'Kelly B, Hynes JP, Mooney A, Dunne J, Ni Cheallaigh C, O'Farrelly C, Bourke NM, Conlon N, Martin-Loeches I, Bergin C, Nadarajan P, Bannan C. Townsend L, et al. Ann Am Thorac Soc. 2021 Jun;18(6):997-1003. doi: 10.1513/AnnalsATS.202009-1175OC. Ann Am Thorac Soc. 2021. PMID: 33413026 Free PMC article.
Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response.
Townsend L, Fogarty H, Dyer A, Martin-Loeches I, Bannan C, Nadarajan P, Bergin C, O'Farrelly C, Conlon N, Bourke NM, Ward SE, Byrne M, Ryan K, O'Connell N, O'Sullivan JM, Ni Cheallaigh C, O'Donnell JS. Townsend L, et al. J Thromb Haemost. 2021 Apr;19(4):1064-1070. doi: 10.1111/jth.15267. Epub 2021 Mar 8. J Thromb Haemost. 2021. PMID: 33587810 Free PMC article.
306 results