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Novel developments in omega-3 fatty acid-based strategies.
Davidson MH, Kling D, Maki KC. Davidson MH, et al. Among authors: kling d. Curr Opin Lipidol. 2011 Dec;22(6):437-44. doi: 10.1097/MOL.0b013e32834bd642. Curr Opin Lipidol. 2011. PMID: 21986642 Review.
A novel omega-3 free fatty acid formulation has dramatically improved bioavailability during a low-fat diet compared with omega-3-acid ethyl esters: the ECLIPSE (Epanova(®) compared to Lovaza(®) in a pharmacokinetic single-dose evaluation) study.
Davidson MH, Johnson J, Rooney MW, Kyle ML, Kling DF. Davidson MH, et al. J Clin Lipidol. 2012 Nov-Dec;6(6):573-84. doi: 10.1016/j.jacl.2012.01.002. Epub 2012 Jan 24. J Clin Lipidol. 2012. PMID: 23312053 Clinical Trial.
IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial.
Ridker PM, Devalaraja M, Baeres FMM, Engelmann MDM, Hovingh GK, Ivkovic M, Lo L, Kling D, Pergola P, Raj D, Libby P, Davidson M; RESCUE Investigators. Ridker PM, et al. Among authors: kling d. Lancet. 2021 May 29;397(10289):2060-2069. doi: 10.1016/S0140-6736(21)00520-1. Epub 2021 May 17. Lancet. 2021. PMID: 34015342 Clinical Trial.
A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial).
Maki KC, Orloff DG, Nicholls SJ, Dunbar RL, Roth EM, Curcio D, Johnson J, Kling D, Davidson MH. Maki KC, et al. Among authors: kling d. Clin Ther. 2013 Sep;35(9):1400-11.e1-3. doi: 10.1016/j.clinthera.2013.07.420. Epub 2013 Aug 30. Clin Ther. 2013. PMID: 23998969 Clinical Trial.
216 results