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Connectivity mapping-based identification of pharmacological inhibitor targeting HDAC6 in aggressive pancreatic ductal adenocarcinoma.
Atri P, Shah A, Natarajan G, Rachagani S, Rauth S, Ganguly K, Carmicheal J, Ghersi D, Cox JL, Smith LM, Jain M, Kumar S, Ponnusamy MP, Seshacharyulu P, Batra SK. Atri P, et al. Among authors: rauth s. NPJ Precis Oncol. 2024 Mar 7;8(1):66. doi: 10.1038/s41698-024-00562-5. NPJ Precis Oncol. 2024. PMID: 38454151 Free PMC article.
Cancer-Associated Fibroblast Induces Acinar-to-Ductal Cell Transdifferentiation and Pancreatic Cancer Initiation Via LAMA5/ITGA4 Axis.
Parte S, Kaur AB, Nimmakayala RK, Ogunleye AO, Chirravuri R, Vengoji R, Leon F, Nallasamy P, Rauth S, Alsafwani ZW, Lele S, Cox JL, Bhat I, Singh S, Batra SK, Ponnusamy MP. Parte S, et al. Among authors: rauth s. Gastroenterology. 2024 May;166(5):842-858.e5. doi: 10.1053/j.gastro.2023.12.018. Epub 2023 Dec 27. Gastroenterology. 2024. PMID: 38154529
Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies.
Shah A, Chaudhary S, Lakshmanan I, Aithal A, Kisling SG, Sorrell C, Marimuthu S, Gautam SK, Rauth S, Kshirsagar P, Cox JL, Natarajan G, Bhatia R, Mallya K, Rachagani S, Nasser MW, Ganti AK, Salgia R, Kumar S, Jain M, Ponnusamy MP, Batra SK. Shah A, et al. Among authors: rauth s. NPJ Precis Oncol. 2023 Aug 11;7(1):74. doi: 10.1038/s41698-023-00423-7. NPJ Precis Oncol. 2023. PMID: 37567918 Free PMC article.
Elevated PAF1-RAD52 axis confers chemoresistance to human cancers.
Rauth S, Ganguly K, Atri P, Parte S, Nimmakayala RK, Varadharaj V, Nallasamy P, Vengoji R, Ogunleye AO, Lakshmanan I, Chirravuri R, Bessho M, Cox JL, Foster JM, Talmon GA, Bessho T, Ganti AK, Batra SK, Ponnusamy MP. Rauth S, et al. Cell Rep. 2023 Feb 28;42(2):112043. doi: 10.1016/j.celrep.2023.112043. Epub 2023 Jan 28. Cell Rep. 2023. PMID: 36709426 Free PMC article.
Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma.
Zhang C, Atri P, Nallasamy P, Parte S, Rauth S, Nimmakayala RK, Marimuthu S, Chirravuri-Venkata R, Bhatia R, Halder S, Shah A, Cox JL, Smith L, Kumar S, Foster JM, Kukreja RC, Seshacharyulu P, Ponnusamy MP, Batra SK. Zhang C, et al. Among authors: rauth s. Cancer Lett. 2022 Dec 28;551:215922. doi: 10.1016/j.canlet.2022.215922. Epub 2022 Sep 19. Cancer Lett. 2022. PMID: 36285687 Free PMC article.
Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma.
Lakshmanan I, Marimuthu S, Chaudhary S, Seshacharyulu P, Rachagani S, Muniyan S, Chirravuri-Venkata R, Atri P, Rauth S, Nimmakayala RK, Siddiqui JA, Gautam SK, Shah A, Natarajan G, Parte S, Bhyravbhatla N, Mallya K, Haridas D, Talmon GA, Smith LM, Kumar S, Ganti AK, Jain M, Ponnusamy MP, Batra SK. Lakshmanan I, et al. Among authors: rauth s. Oncogene. 2022 Nov;41(48):5147-5159. doi: 10.1038/s41388-022-02493-6. Epub 2022 Oct 21. Oncogene. 2022. PMID: 36271032 Free PMC article.
56 results