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Design of protein-binding proteins from the target structure alone.
Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24.
Nature. 2022.
PMID: 35332283
Free PMC article.
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D.
Cao L, et al. Among authors: kozodoy l.
Science. 2020 Oct 23;370(6515):426-431. doi: 10.1126/science.abd9909. Epub 2020 Sep 9.
Science. 2020.
PMID: 32907861
Free PMC article.
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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls L, Park YJ, Stewart L, Diamond M, Veesler D, Baker D.
Cao L, et al. Among authors: kozodoy l.
bioRxiv [Preprint]. 2020 Aug 3:2020.08.03.234914. doi: 10.1101/2020.08.03.234914.
bioRxiv. 2020.
PMID: 32793905
Free PMC article.
Updated.
Preprint.
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Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken SE, Ljubetič A, Edman N, Ueda G, Chow CM, Johnson M, Addetia A, Navarro MJ, Panpradist N, Gale M Jr, Freedman BS, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D.
Hunt AC, et al. Among authors: kozodoy l.
Sci Transl Med. 2022 May 25;14(646):eabn1252. doi: 10.1126/scitranslmed.abn1252. Epub 2022 May 25.
Sci Transl Med. 2022.
PMID: 35412328
Free PMC article.
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Multivalent designed proteins protect against SARS-CoV-2 variants of concern.
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger-Gericke A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken S, Ljubetič A, Edman N, Ueda G, Chow C, Addetia A, Panpradist N, Gale M Jr, Freedman BS, Lutz BR, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D.
Hunt AC, et al. Among authors: kozodoy l.
bioRxiv [Preprint]. 2021 Jul 7:2021.07.07.451375. doi: 10.1101/2021.07.07.451375.
bioRxiv. 2021.
PMID: 34268509
Free PMC article.
Updated.
Preprint.
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