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Spatial CRISPR genomics identifies regulators of the tumor microenvironment.
Dhainaut M, Rose SA, Akturk G, Wroblewska A, Nielsen SR, Park ES, Buckup M, Roudko V, Pia L, Sweeney R, Le Berichel J, Wilk CM, Bektesevic A, Lee BH, Bhardwaj N, Rahman AH, Baccarini A, Gnjatic S, Pe'er D, Merad M, Brown BD. Dhainaut M, et al. Among authors: nielsen sr. Cell. 2022 Mar 31;185(7):1223-1239.e20. doi: 10.1016/j.cell.2022.02.015. Epub 2022 Mar 14. Cell. 2022. PMID: 35290801 Free PMC article.
Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade.
Nielsen SR, Strøbech JE, Horton ER, Jackstadt R, Laitala A, Bravo MC, Maltese G, Jensen ARD, Reuten R, Rafaeva M, Karim SA, Hwang CI, Arnes L, Tuveson DA, Sansom OJ, Morton JP, Erler JT. Nielsen SR, et al. Nat Commun. 2021 Jun 7;12(1):3414. doi: 10.1038/s41467-021-23731-7. Nat Commun. 2021. PMID: 34099731 Free PMC article.
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Ireland L, Santos A, Ahmed MS, Rainer C, Nielsen SR, Quaranta V, Weyer-Czernilofsky U, Engle DD, Perez-Mancera PA, Coupland SE, Taktak A, Bogenrieder T, Tuveson DA, Campbell F, Schmid MC, Mielgo A. Ireland L, et al. Among authors: nielsen sr. Cancer Res. 2016 Dec 1;76(23):6851-6863. doi: 10.1158/0008-5472.CAN-16-1201. Epub 2016 Oct 14. Cancer Res. 2016. PMID: 27742686 Free PMC article.
Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor.
Rafaeva M, Horton ER, Jensen ARD, Madsen CD, Reuten R, Willacy O, Brøchner CB, Jensen TH, Zornhagen KW, Crespo M, Grønseth DS, Nielsen SR, Idorn M, Straten PT, Rohrberg K, Spanggaard I, Højgaard M, Lassen U, Erler JT, Mayorca-Guiliani AE. Rafaeva M, et al. Among authors: nielsen sr. Adv Healthc Mater. 2022 Jan;11(1):e2100684. doi: 10.1002/adhm.202100684. Epub 2021 Nov 17. Adv Healthc Mater. 2022. PMID: 34734500
29 results