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Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application.
Echle A, Ghaffari Laleh N, Quirke P, Grabsch HI, Muti HS, Saldanha OL, Brockmoeller SF, van den Brandt PA, Hutchins GGA, Richman SD, Horisberger K, Galata C, Ebert MP, Eckardt M, Boutros M, Horst D, Reissfelder C, Alwers E, Brinker TJ, Langer R, Jenniskens JCA, Offermans K, Mueller W, Gray R, Gruber SB, Greenson JK, Rennert G, Bonner JD, Schmolze D, Chang-Claude J, Brenner H, Trautwein C, Boor P, Jaeger D, Gaisa NT, Hoffmeister M, West NP, Kather JN. Echle A, et al. Among authors: trautwein c. ESMO Open. 2022 Apr;7(2):100400. doi: 10.1016/j.esmoop.2022.100400. Epub 2022 Mar 2. ESMO Open. 2022. PMID: 35247870 Free PMC article.
A liver nodule in a patient transplanted for primary sclerosing cholangitis: an interdisciplinary diagnostic approach.
Loosen SH, Schmeding M, Roderburg C, Binnebösel M, Temizel I, Mottaghy FM, Tischendorf JJ, Tacke F, Gaisa NT, Hussein K, Lehmann U, Trautwein C, Neumann UP, Luedde T. Loosen SH, et al. Among authors: trautwein c. Z Gastroenterol. 2017 Jan;55(1):56-62. doi: 10.1055/s-0042-111048. Epub 2016 Oct 5. Z Gastroenterol. 2017. PMID: 27706546 English.
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.
Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T. Kather JN, et al. Among authors: trautwein c. Nat Med. 2019 Jul;25(7):1054-1056. doi: 10.1038/s41591-019-0462-y. Epub 2019 Jun 3. Nat Med. 2019. PMID: 31160815 Free PMC article.
Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.
Echle A, Grabsch HI, Quirke P, van den Brandt PA, West NP, Hutchins GGA, Heij LR, Tan X, Richman SD, Krause J, Alwers E, Jenniskens J, Offermans K, Gray R, Brenner H, Chang-Claude J, Trautwein C, Pearson AT, Boor P, Luedde T, Gaisa NT, Hoffmeister M, Kather JN. Echle A, et al. Among authors: trautwein c. Gastroenterology. 2020 Oct;159(4):1406-1416.e11. doi: 10.1053/j.gastro.2020.06.021. Epub 2020 Jun 17. Gastroenterology. 2020. PMID: 32562722 Free PMC article.
Deep learning detects genetic alterations in cancer histology generated by adversarial networks.
Krause J, Grabsch HI, Kloor M, Jendrusch M, Echle A, Buelow RD, Boor P, Luedde T, Brinker TJ, Trautwein C, Pearson AT, Quirke P, Jenniskens J, Offermans K, van den Brandt PA, Kather JN. Krause J, et al. Among authors: trautwein c. J Pathol. 2021 May;254(1):70-79. doi: 10.1002/path.5638. Epub 2021 Mar 16. J Pathol. 2021. PMID: 33565124 Free article.
Pan-cancer image-based detection of clinically actionable genetic alterations.
Kather JN, Heij LR, Grabsch HI, Loeffler C, Echle A, Muti HS, Krause J, Niehues JM, Sommer KAJ, Bankhead P, Kooreman LFS, Schulte JJ, Cipriani NA, Buelow RD, Boor P, Ortiz-Brüchle NN, Hanby AM, Speirs V, Kochanny S, Patnaik A, Srisuwananukorn A, Brenner H, Hoffmeister M, van den Brandt PA, Jäger D, Trautwein C, Pearson AT, Luedde T. Kather JN, et al. Among authors: trautwein c. Nat Cancer. 2020 Aug;1(8):789-799. doi: 10.1038/s43018-020-0087-6. Epub 2020 Jul 27. Nat Cancer. 2020. PMID: 33763651 Free PMC article.
Artificial Intelligence-based Detection of FGFR3 Mutational Status Directly from Routine Histology in Bladder Cancer: A Possible Preselection for Molecular Testing?
Loeffler CML, Ortiz Bruechle N, Jung M, Seillier L, Rose M, Laleh NG, Knuechel R, Brinker TJ, Trautwein C, Gaisa NT, Kather JN. Loeffler CML, et al. Among authors: trautwein c. Eur Urol Focus. 2022 Mar;8(2):472-479. doi: 10.1016/j.euf.2021.04.007. Epub 2021 Apr 22. Eur Urol Focus. 2022. PMID: 33895087 Free article.
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study.
Muti HS, Heij LR, Keller G, Kohlruss M, Langer R, Dislich B, Cheong JH, Kim YW, Kim H, Kook MC, Cunningham D, Allum WH, Langley RE, Nankivell MG, Quirke P, Hayden JD, West NP, Irvine AJ, Yoshikawa T, Oshima T, Huss R, Grosser B, Roviello F, d'Ignazio A, Quaas A, Alakus H, Tan X, Pearson AT, Luedde T, Ebert MP, Jäger D, Trautwein C, Gaisa NT, Grabsch HI, Kather JN. Muti HS, et al. Among authors: trautwein c. Lancet Digit Health. 2021 Oct;3(10):e654-e664. doi: 10.1016/S2589-7500(21)00133-3. Epub 2021 Aug 17. Lancet Digit Health. 2021. PMID: 34417147 Free PMC article.
Weakly supervised annotation-free cancer detection and prediction of genotype in routine histopathology.
Schrammen PL, Ghaffari Laleh N, Echle A, Truhn D, Schulz V, Brinker TJ, Brenner H, Chang-Claude J, Alwers E, Brobeil A, Kloor M, Heij LR, Jäger D, Trautwein C, Grabsch HI, Quirke P, West NP, Hoffmeister M, Kather JN. Schrammen PL, et al. Among authors: trautwein c. J Pathol. 2022 Jan;256(1):50-60. doi: 10.1002/path.5800. Epub 2021 Oct 22. J Pathol. 2022. PMID: 34561876 Free article.
844 results