Sakamoto KM - Search Results

1

Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia.

Zhang K, Horikoshi N, Li S, Powers AS, Hameedi MA, Pintilie GD, Chae HD, Khan YA, Suomivuori CM, Dror RO, Sakamoto KM, Chiu W, Wakatsuki S. Zhang K, et al. Among authors: sakamoto km. ACS Cent Sci. 2022 Feb 23;8(2):214-222. doi: 10.1021/acscentsci.1c01090. Epub 2022 Feb 7. ACS Cent Sci. 2022. PMID: 35233453 Free PMC article.

2

Small molecule screen for inhibitors of expression from canonical CREB response element-containing promoters.

Mitton B, Hsu K, Dutta R, Tiu BC, Cox N, McLure KG, Chae HD, Smith M, Eklund EA, Solow-Cordero DE, Sakamoto KM. Mitton B, et al. Among authors: sakamoto km. Oncotarget. 2016 Feb 23;7(8):8653-62. doi: 10.18632/oncotarget.7085. Oncotarget. 2016. PMID: 26840025 Free PMC article.

3

Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways.

Chae HD, Cox N, Dahl GV, Lacayo NJ, Davis KL, Capolicchio S, Smith M, Sakamoto KM. Chae HD, et al. Among authors: sakamoto km. Oncotarget. 2017 Dec 31;9(4):4301-4317. doi: 10.18632/oncotarget.23794. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435104 Free PMC article.

4

CBP Modulates Sensitivity to Dasatinib in Pre-BCR⁺ Acute Lymphoblastic Leukemia.

Duque-Afonso J, Lin CH, Han K, Morgens DW, Jeng EE, Weng Z, Jeong J, Wong SHK, Zhu L, Wei MC, Chae HD, Schrappe M, Cario G, Duyster J, Xiao X, Sakamoto KM, Bassik MC, Cleary ML. Duque-Afonso J, et al. Among authors: sakamoto km. Cancer Res. 2018 Nov 15;78(22):6497-6508. doi: 10.1158/0008-5472.CAN-18-1703. Epub 2018 Sep 27. Cancer Res. 2018. PMID: 30262461 Free PMC article.

5

SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathway.

Chae HD, Cox N, Capolicchio S, Lee JW, Horikoshi N, Kam S, Ng AA, Edwards J, Butler TL, Chan J, Lee Y, Potter G, Capece MC, Liu CW, Wakatsuki S, Smith M, Sakamoto KM. Chae HD, et al. Among authors: sakamoto km. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2307-2315. doi: 10.1016/j.bmcl.2019.06.023. Epub 2019 Jun 19. Bioorg Med Chem Lett. 2019. PMID: 31253529

6

MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways.

Youn M, Huang H, Chen C, Kam S, Wilkes MC, Chae HD, Sridhar KJ, Greenberg PL, Glader B, Narla A, Lin S, Sakamoto KM. Youn M, et al. Among authors: sakamoto km. Blood Adv. 2019 Sep 24;3(18):2751-2763. doi: 10.1182/bloodadvances.2019000537. Blood Adv. 2019. PMID: 31540902 Free PMC article.

7

Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit?

Wojcicki AV, Kadapakkam M, Frymoyer A, Lacayo N, Chae HD, Sakamoto KM. Wojcicki AV, et al. Among authors: sakamoto km. Cancers (Basel). 2020 Feb 13;12(2):441. doi: 10.3390/cancers12020441. Cancers (Basel). 2020. PMID: 32069925 Free PMC article. Review.

8

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit.

Chae HD, Dutta R, Tiu B, Hoff FW, Accordi B, Serafin V, Youn M, Huang M, Sumarsono N, Davis KL, Lacayo NJ, Pigazzi M, Horton TM, Kornblau SM, Sakamoto KM. Chae HD, et al. Among authors: sakamoto km. Oncotarget. 2020 Jun 23;11(25):2387-2403. doi: 10.18632/oncotarget.27630. eCollection 2020 Jun 23. Oncotarget. 2020. PMID: 32637030 Free PMC article.

9

SATB1 Chromatin Loops Regulate Megakaryocyte/Erythroid Progenitor Expansion by Facilitating HSP70 and GATA1 Induction.

Wilkes MC, Chae HD, Scanlon V, Cepika AM, Wentworth EP, Saxena M, Eskin A, Chen Z, Glader B, Grazia Roncarolo M, Nelson SF, Sakamoto KM. Wilkes MC, et al. Among authors: sakamoto km. Stem Cells. 2023 Jun 15;41(6):560-569. doi: 10.1093/stmcls/sxad025. Stem Cells. 2023. PMID: 36987811 Free PMC article.

10

RSK Isoforms in Acute Myeloid Leukemia.

Youn M, Gomez JO, Mark K, Sakamoto KM. Youn M, et al. Among authors: sakamoto km. Biomedicines. 2021 Jun 24;9(7):726. doi: 10.3390/biomedicines9070726. Biomedicines. 2021. PMID: 34202904 Free PMC article. Review.

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