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STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity.
Borba JVB, Alves VM, Braga RC, Korn DR, Overdahl K, Silva AC, Hall SUS, Overdahl E, Kleinstreuer N, Strickland J, Allen D, Andrade CH, Muratov EN, Tropsha A. Borba JVB, et al. Among authors: kleinstreuer n. Environ Health Perspect. 2022 Feb;130(2):27012. doi: 10.1289/EHP9341. Epub 2022 Feb 22. Environ Health Perspect. 2022. PMID: 35192406 Free PMC article.
Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization.
Alves VM, Muratov E, Fourches D, Strickland J, Kleinstreuer N, Andrade CH, Tropsha A. Alves VM, et al. Among authors: kleinstreuer n. Toxicol Appl Pharmacol. 2015 Apr 15;284(2):273-80. doi: 10.1016/j.taap.2014.12.013. Epub 2015 Jan 3. Toxicol Appl Pharmacol. 2015. PMID: 25560673 Free PMC article.
A Curated Database of Rodent Uterotrophic Bioactivity.
Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Chang X, Hamm JT, Casey WM. Kleinstreuer NC, et al. Environ Health Perspect. 2016 May;124(5):556-62. doi: 10.1289/ehp.1510183. Epub 2015 Oct 2. Environ Health Perspect. 2016. PMID: 26431337 Free PMC article. Review.
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: kleinstreuer n. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Multivariate models for prediction of human skin sensitization hazard.
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, Matheson J, Jacobs A, Casey W, Kleinstreuer N. Strickland J, et al. Among authors: kleinstreuer n. J Appl Toxicol. 2017 Mar;37(3):347-360. doi: 10.1002/jat.3366. Epub 2016 Aug 2. J Appl Toxicol. 2017. PMID: 27480324 Free PMC article.
Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations.
Miller MF, Goodson WH, Manjili MH, Kleinstreuer N, Bisson WH, Lowe L. Miller MF, et al. Among authors: kleinstreuer n. Environ Health Perspect. 2017 Feb;125(2):163-169. doi: 10.1289/EHP411. Epub 2016 Aug 12. Environ Health Perspect. 2017. PMID: 27517672 Free PMC article.
The restructuring of many existing regulatory frameworks will require adequate testing of relevant environmental mixtures to build a critical mass of evidence on which to base policy decisions. Citation: Miller MF, Goodson WH III, Manjili MH, Kleinstreuer N, Bisson …
The restructuring of many existing regulatory frameworks will require adequate testing of relevant environmental mixtures to build a critica …
Development and Validation of a Computational Model for Androgen Receptor Activity.
Kleinstreuer NC, Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM, Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. Kleinstreuer NC, et al. Chem Res Toxicol. 2017 Apr 17;30(4):946-964. doi: 10.1021/acs.chemrestox.6b00347. Epub 2016 Dec 9. Chem Res Toxicol. 2017. PMID: 27933809 Free PMC article.
153 results