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STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity.
Borba JVB, Alves VM, Braga RC, Korn DR, Overdahl K, Silva AC, Hall SUS, Overdahl E, Kleinstreuer N, Strickland J, Allen D, Andrade CH, Muratov EN, Tropsha A. Borba JVB, et al. Among authors: allen d. Environ Health Perspect. 2022 Feb;130(2):27012. doi: 10.1289/EHP9341. Epub 2022 Feb 22. Environ Health Perspect. 2022. PMID: 35192406 Free PMC article.
A Curated Database of Rodent Uterotrophic Bioactivity.
Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Chang X, Hamm JT, Casey WM. Kleinstreuer NC, et al. Environ Health Perspect. 2016 May;124(5):556-62. doi: 10.1289/ehp.1510183. Epub 2015 Oct 2. Environ Health Perspect. 2016. PMID: 26431337 Free PMC article. Review.
Adverse outcome pathways: From research to regulation scientific workshop report.
Kleinstreuer NC, Sullivan K, Allen D, Edwards S, Mendrick DL, Embry M, Matheson J, Rowlands JC, Munn S, Maull E, Casey W. Kleinstreuer NC, et al. Among authors: allen d. Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14. Regul Toxicol Pharmacol. 2016. PMID: 26774756 Free PMC article.
Integrated decision strategies for skin sensitization hazard.
Strickland J, Zang Q, Kleinstreuer N, Paris M, Lehmann DM, Choksi N, Matheson J, Jacobs A, Lowit A, Allen D, Casey W. Strickland J, et al. Among authors: allen d. J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6. J Appl Toxicol. 2016. PMID: 26851134 Free PMC article.
Multivariate models for prediction of human skin sensitization hazard.
Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, Matheson J, Jacobs A, Casey W, Kleinstreuer N. Strickland J, et al. Among authors: allen d. J Appl Toxicol. 2017 Mar;37(3):347-360. doi: 10.1002/jat.3366. Epub 2016 Aug 2. J Appl Toxicol. 2017. PMID: 27480324 Free PMC article.
Development and Validation of a Computational Model for Androgen Receptor Activity.
Kleinstreuer NC, Ceger P, Watt ED, Martin M, Houck K, Browne P, Thomas RS, Casey WM, Dix DJ, Allen D, Sakamuru S, Xia M, Huang R, Judson R. Kleinstreuer NC, et al. Among authors: allen d. Chem Res Toxicol. 2017 Apr 17;30(4):946-964. doi: 10.1021/acs.chemrestox.6b00347. Epub 2016 Dec 9. Chem Res Toxicol. 2017. PMID: 27933809 Free PMC article.
Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Among authors: allen d. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
Prediction of skin sensitization potency using machine learning approaches.
Zang Q, Paris M, Lehmann DM, Bell S, Kleinstreuer N, Allen D, Matheson J, Jacobs A, Casey W, Strickland J. Zang Q, et al. Among authors: allen d. J Appl Toxicol. 2017 Jul;37(7):792-805. doi: 10.1002/jat.3424. Epub 2017 Jan 10. J Appl Toxicol. 2017. PMID: 28074598 Free PMC article.
An Integrated Chemical Environment to Support 21st-Century Toxicology.
Bell SM, Phillips J, Sedykh A, Tandon A, Sprankle C, Morefield SQ, Shapiro A, Allen D, Shah R, Maull EA, Casey WM, Kleinstreuer NC. Bell SM, et al. Among authors: allen d. Environ Health Perspect. 2017 May 25;125(5):054501. doi: 10.1289/EHP1759. Environ Health Perspect. 2017. PMID: 28557712 Free PMC article.
3,937 results