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Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W; Alzheimer's Disease Genetics Consortium; Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Jun GR, et al. Among authors: ikezu t. Alzheimers Dement. 2022 Nov;18(11):2042-2054. doi: 10.1002/alz.12607. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142023 Free PMC article.
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. Jun G, et al. Among authors: ikezu t. Ann Neurol. 2014 Sep;76(3):379-92. doi: 10.1002/ana.24219. Epub 2014 Jul 29. Ann Neurol. 2014. PMID: 25043464 Free PMC article.
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues.
Muraoka S, DeLeo AM, Sethi MK, Yukawa-Takamatsu K, Yang Z, Ko J, Hogan JD, Ruan Z, You Y, Wang Y, Medalla M, Ikezu S, Chen M, Xia W, Gorantla S, Gendelman HE, Issadore D, Zaia J, Ikezu T. Muraoka S, et al. Among authors: ikezu s, ikezu t. Alzheimers Dement. 2020 Jun;16(6):896-907. doi: 10.1002/alz.12089. Epub 2020 Apr 17. Alzheimers Dement. 2020. PMID: 32301581 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34971140
Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain.
You Y, Muraoka S, Jedrychowski MP, Hu J, McQuade AK, Young-Pearse T, Aslebagh R, Shaffer SA, Gygi SP, Blurton-Jones M, Poon WW, Ikezu T. You Y, et al. Among authors: ikezu t. J Extracell Vesicles. 2022 Jan;11(1):e12183. doi: 10.1002/jev2.12183. J Extracell Vesicles. 2022. PMID: 35029059 Free PMC article.
141 results