Meng G - Search Results

1

Rational Design and Synthesis of 3-Morpholine Linked Aromatic-Imino-1H-Indoles as Novel Kv1.5 Channel Inhibitors Sharing Vasodilation Effects.

Qin W, Li YH, Tong J, Wu J, Zhao D, Li HJ, Xing L, He CX, Zhou X, Li PQ, Meng G, Wu SP, Cao HL. Qin W, et al. Among authors: meng g. Front Mol Biosci. 2022 Jan 24;8:805594. doi: 10.3389/fmolb.2021.805594. eCollection 2021. Front Mol Biosci. 2022. PMID: 35141279 Free PMC article.

2

Design and synthesis of new potent PTP1B inhibitors with the skeleton of 2-substituted imino-3-substituted-5-heteroarylidene-1,3-thiazolidine-4-one: Part I.

Meng G, Zheng M, Wang M, Tong J, Ge W, Zhang J, Zheng A, Li J, Gao L, Li J. Meng G, et al. Eur J Med Chem. 2016 Oct 21;122:756-769. doi: 10.1016/j.ejmech.2016.05.060. Epub 2016 May 28. Eur J Med Chem. 2016. PMID: 27526040

3

Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine.

Jin K, Sang Y, De Clercq E, Pannecouque C, Meng G. Jin K, et al. Among authors: meng g. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3491-3495. doi: 10.1016/j.bmcl.2018.10.010. Epub 2018 Oct 9. Bioorg Med Chem Lett. 2018. PMID: 30318436

4

Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.

Jin K, Liu M, Zhuang C, De Clercq E, Pannecouque C, Meng G, Chen F. Jin K, et al. Among authors: meng g. Acta Pharm Sin B. 2020 Feb;10(2):344-357. doi: 10.1016/j.apsb.2019.09.007. Epub 2019 Oct 17. Acta Pharm Sin B. 2020. PMID: 32082978 Free PMC article.

5

Structure-Based Design of Novel Thiazolone[3,2-a]pyrimidine Derivatives as Potent RNase H Inhibitors for HIV Therapy.

Zhu XD, Corona A, Maloccu S, Tramontano E, Wang S, Pannecouque C, De Clercq E, Meng G, Chen FE. Zhu XD, et al. Among authors: meng g. Molecules. 2024 May 3;29(9):2120. doi: 10.3390/molecules29092120. Molecules. 2024. PMID: 38731613 Free PMC article.

6

Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors.

Liu Y, Meng G, Zheng A, Chen F, Chen W, De Clercq E, Pannecouque C, Balzarini J. Liu Y, et al. Among authors: meng g. Eur J Pharm Sci. 2014 Oct 1;62:334-41. doi: 10.1016/j.ejps.2014.06.003. Epub 2014 Jun 20. Eur J Pharm Sci. 2014. PMID: 24956462

7

Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors.

Meng G, Liu Y, Zheng A, Chen F, Chen W, De Clercq E, Pannecouque C, Balzarini J. Meng G, et al. Eur J Med Chem. 2014 Jul 23;82:600-11. doi: 10.1016/j.ejmech.2014.05.059. Epub 2014 Jun 5. Eur J Med Chem. 2014. PMID: 24952305

8

Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains.

Jin K, Sang Y, Han S, De Clercq E, Pannecouque C, Meng G, Chen F. Jin K, et al. Among authors: meng g. Eur J Med Chem. 2019 Aug 15;176:11-20. doi: 10.1016/j.ejmech.2019.05.011. Epub 2019 May 10. Eur J Med Chem. 2019. PMID: 31091477

9

Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1.

Jin K, Yin H, De Clercq E, Pannecouque C, Meng G, Chen F. Jin K, et al. Among authors: meng g. Eur J Med Chem. 2018 Feb 10;145:726-734. doi: 10.1016/j.ejmech.2018.01.016. Epub 2018 Jan 8. Eur J Med Chem. 2018. PMID: 29353724

10

Development of fluorine-substituted NH₂-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability.

Jin X, Wang S, Zhao L, Huang W, Zhang Y, Pannecouque C, De Clercq E, Meng G, Piao H, Chen F. Jin X, et al. Among authors: meng g. Acta Pharm Sin B. 2023 Mar;13(3):1192-1203. doi: 10.1016/j.apsb.2022.08.017. Epub 2022 Aug 27. Acta Pharm Sin B. 2023. PMID: 36970200 Free PMC article.

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