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Hot-Spot Residues to be Mutated Common in G Protein-Coupled Receptors of Class A: Identification of Thermostabilizing Mutations Followed by Determination of Three-Dimensional Structures for Two Example Receptors.
Yasuda S, Kajiwara Y, Toyoda Y, Morimoto K, Suno R, Iwata S, Kobayashi T, Murata T, Kinoshita M. Yasuda S, et al. Among authors: murata t. J Phys Chem B. 2017 Jul 6;121(26):6341-6350. doi: 10.1021/acs.jpcb.7b02997. Epub 2017 Jun 23. J Phys Chem B. 2017. PMID: 28644022
Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor.
Suno R, Lee S, Maeda S, Yasuda S, Yamashita K, Hirata K, Horita S, Tawaramoto MS, Tsujimoto H, Murata T, Kinoshita M, Yamamoto M, Kobilka BK, Vaidehi N, Iwata S, Kobayashi T. Suno R, et al. Among authors: murata t. Nat Chem Biol. 2018 Dec;14(12):1150-1158. doi: 10.1038/s41589-018-0152-y. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420692 Free PMC article.
Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface.
Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K, Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T. Toyoda Y, et al. Among authors: murata t. Nat Chem Biol. 2019 Jan;15(1):18-26. doi: 10.1038/s41589-018-0131-3. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510193
Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained.
Yasuda S, Akiyama T, Nemoto S, Hayashi T, Ueta T, Kojima K, Tsukamoto T, Nagatoishi S, Tsumoto K, Sudo Y, Kinoshita M, Murata T. Yasuda S, et al. Among authors: murata t. J Chem Inf Model. 2020 Mar 23;60(3):1709-1716. doi: 10.1021/acs.jcim.0c00063. Epub 2020 Mar 10. J Chem Inf Model. 2020. PMID: 32155058
2,770 results