Cai H - Search Results

1

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice.

Yang C, Qiao T, Yu J, Wang H, Guo Y, Salameh J, Metterville J, Parsi S, Yusuf I, Brown RH, Cai H, Xu Z. Yang C, et al. Among authors: cai h. PLoS One. 2022 Feb 3;17(2):e0255710. doi: 10.1371/journal.pone.0255710. eCollection 2022. PLoS One. 2022. PMID: 35113871 Free PMC article.

2

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress.

Cai H, Lin X, Xie C, Laird FM, Lai C, Wen H, Chiang HC, Shim H, Farah MH, Hoke A, Price DL, Wong PC. Cai H, et al. J Neurosci. 2005 Aug 17;25(33):7567-74. doi: 10.1523/JNEUROSCI.1645-05.2005. J Neurosci. 2005. PMID: 16107644 Free PMC article.

3

Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.

Lin X, Parisiadou L, Sgobio C, Liu G, Yu J, Sun L, Shim H, Gu XL, Luo J, Long CX, Ding J, Mateo Y, Sullivan PH, Wu LG, Goldstein DS, Lovinger D, Cai H. Lin X, et al. Among authors: cai h. J Neurosci. 2012 Jul 4;32(27):9248-64. doi: 10.1523/JNEUROSCI.1731-12.2012. J Neurosci. 2012. PMID: 22764233 Free PMC article.

4

MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.

Cho HJ, Liu G, Jin SM, Parisiadou L, Xie C, Yu J, Sun L, Ma B, Ding J, Vancraenenbroeck R, Lobbestael E, Baekelandt V, Taymans JM, He P, Troncoso JC, Shen Y, Cai H. Cho HJ, et al. Among authors: cai h. Hum Mol Genet. 2013 Feb 1;22(3):608-20. doi: 10.1093/hmg/dds470. Epub 2012 Nov 2. Hum Mol Genet. 2013. PMID: 23125283 Free PMC article.

5

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons.

Aliaga L, Lai C, Yu J, Chub N, Shim H, Sun L, Xie C, Yang WJ, Lin X, O'Donovan MJ, Cai H. Aliaga L, et al. Among authors: cai h. Hum Mol Genet. 2013 Nov 1;22(21):4293-305. doi: 10.1093/hmg/ddt279. Epub 2013 Jun 13. Hum Mol Genet. 2013. PMID: 23771029 Free PMC article.

6

Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis.

Yang C, Wang H, Qiao T, Yang B, Aliaga L, Qiu L, Tan W, Salameh J, McKenna-Yasek DM, Smith T, Peng L, Moore MJ, Brown RH Jr, Cai H, Xu Z. Yang C, et al. Among authors: cai h. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1121-9. doi: 10.1073/pnas.1322641111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616503 Free PMC article.

7

A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.

Luo J, Sun L, Lin X, Liu G, Yu J, Parisiadou L, Xie C, Ding J, Cai H. Luo J, et al. Among authors: cai h. Hum Mol Genet. 2014 Dec 15;23(24):6567-74. doi: 10.1093/hmg/ddu377. Epub 2014 Jul 22. Hum Mol Genet. 2014. PMID: 25051958 Free PMC article.

8

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

Liu G, Sgobio C, Gu X, Sun L, Lin X, Yu J, Parisiadou L, Xie C, Sastry N, Ding J, Lohr KM, Miller GW, Mateo Y, Lovinger DM, Cai H. Liu G, et al. Among authors: cai h. Hum Mol Genet. 2015 Sep 15;24(18):5299-312. doi: 10.1093/hmg/ddv249. Epub 2015 Jun 29. Hum Mol Genet. 2015. PMID: 26123485 Free PMC article.

9

Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation.

Ma B, Yu J, Xie C, Sun L, Lin S, Ding J, Luo J, Cai H. Ma B, et al. Among authors: cai h. J Neurosci. 2015 Jul 29;35(30):10799-814. doi: 10.1523/JNEUROSCI.2455-14.2015. J Neurosci. 2015. PMID: 26224862 Free PMC article.

10

Genetic ablation of dynactin p150^Glued in postnatal neurons causes preferential degeneration of spinal motor neurons in aged mice.

Yu J, Lai C, Shim H, Xie C, Sun L, Long CX, Ding J, Li Y, Cai H. Yu J, et al. Among authors: cai h. Mol Neurodegener. 2018 Mar 1;13(1):10. doi: 10.1186/s13024-018-0242-z. Mol Neurodegener. 2018. PMID: 29490687 Free PMC article.

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