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Pro108Ser mutation of SARS-CoV-2 3CLpro reduces the enzyme activity and ameliorates the clinical severity of COVID-19.
Abe K, Kabe Y, Uchiyama S, Iwasaki YW, Ishizu H, Uwamino Y, Takenouchi T, Uno S, Ishii M, Maruno T, Noda M, Murata M, Hasegawa N, Saya H, Kitagawa Y, Fukunaga K, Amagai M, Siomi H, Suematsu M, Kosaki K; Keio Donner Project. Abe K, et al. Among authors: siomi h. Sci Rep. 2022 Jan 25;12(1):1299. doi: 10.1038/s41598-022-05424-3. Sci Rep. 2022. PMID: 35079088 Free PMC article.
Gatekeepers for Piwi-piRNA complexes to enter the nucleus.
Ishizu H, Nagao A, Siomi H. Ishizu H, et al. Among authors: siomi h. Curr Opin Genet Dev. 2011 Aug;21(4):484-90. doi: 10.1016/j.gde.2011.05.001. Epub 2011 Jul 18. Curr Opin Genet Dev. 2011. PMID: 21764576 Review.
miRNA regulatory ecosystem in early development.
Iwasaki YW, Siomi H. Iwasaki YW, et al. Among authors: siomi h. Mol Cell. 2014 Dec 4;56(5):615-6. doi: 10.1016/j.molcel.2014.11.010. Mol Cell. 2014. PMID: 25479636 Free article.
PIWI-Interacting RNA: Its Biogenesis and Functions.
Iwasaki YW, Siomi MC, Siomi H. Iwasaki YW, et al. Among authors: siomi h, siomi mc. Annu Rev Biochem. 2015;84:405-33. doi: 10.1146/annurev-biochem-060614-034258. Epub 2015 Mar 5. Annu Rev Biochem. 2015. PMID: 25747396 Review.
140 results