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Carboxylated, heteroaryl-substituted chalcones as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
Meng CQ, Ni L, Worsencroft KJ, Ye Z, Weingarten MD, Simpson JE, Skudlarek JW, Marino EM, Suen KL, Kunsch C, Souder A, Howard RB, Sundell CL, Wasserman MA, Sikorski JA. Meng CQ, et al. Among authors: sundell cl. J Med Chem. 2007 Mar 22;50(6):1304-15. doi: 10.1021/jm0614230. Epub 2007 Feb 27. J Med Chem. 2007. PMID: 17323940
AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression.
Kunsch C, Luchoomun J, Chen XL, Dodd GL, Karu KS, Meng CQ, Marino EM, Olliff LK, Piper JD, Qiu FH, Sikorski JA, Somers PK, Suen KL, Thomas S, Whalen AM, Wasserman MA, Sundell CL. Kunsch C, et al. Among authors: sundell cl. J Pharmacol Exp Ther. 2005 May;313(2):492-501. doi: 10.1124/jpet.104.080804. Epub 2005 Feb 8. J Pharmacol Exp Ther. 2005. PMID: 15701708
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
Meng CQ, Somers PK, Hoong LK, Zheng XS, Ye Z, Worsencroft KJ, Simpson JE, Hotema MR, Weingarten MD, MacDOnald ML, Hill RR, Marino EM, Suen KL, Luchoomun J, Kunsch C, Landers LK, Stefanopoulos D, Howard RB, Sundell CL, Saxena U, Wasserman MA, Sikorski JA. Meng CQ, et al. Among authors: sundell cl. J Med Chem. 2004 Dec 2;47(25):6420-32. doi: 10.1021/jm049685u. J Med Chem. 2004. PMID: 15566311
Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis.
Meng CQ, Somers PK, Rachita CL, Holt LA, Hoong LK, Zheng XS, Simpson JE, Hill RR, Olliff LK, Kunsch C, Sundell CL, Parthasarathy S, Saxena U, Sikorski JA, Wasserman MA. Meng CQ, et al. Among authors: sundell cl. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2545-8. doi: 10.1016/s0960-894x(02)00516-4. Bioorg Med Chem Lett. 2002. PMID: 12182856
29 results