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Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma.
do Nascimento RP, Dos Santos BL, Amparo JAO, Soares JRP, da Silva KC, Santana MR, Almeida ÁMAN, da Silva VDA, Costa MFD, Ulrich H, Moura-Neto V, Lopes GPF, Costa SL. do Nascimento RP, et al. Among authors: da silva vda. Pharmaceutics. 2022 Jan 4;14(1):116. doi: 10.3390/pharmaceutics14010116. Pharmaceutics. 2022. PMID: 35057010 Free PMC article. Review.
Alkene lactones from Persea fulva (Lauraceae): Evaluation of their effects on tumor cell growth in vitro and molecular docking studies.
Reis IMA, Conceição RS, Ferreira RS, Dos Santos CC, da Silva GR, de Mattos Oliveira L, Cassiano DSA, Dos Santos Junior MC, Botura MB, da Silva VDA, Costa SL, da Silva TMS, Vieira IJC, Braz-Filho R, Branco A. Reis IMA, et al. Among authors: da silva vda, da silva gr, da silva tms. Bioorg Chem. 2019 May;86:665-673. doi: 10.1016/j.bioorg.2019.02.023. Epub 2019 Feb 14. Bioorg Chem. 2019. PMID: 30826627
Lupeol inhibits LPS-induced neuroinflammation in cerebellar cultures and induces neuroprotection associated to the modulation of astrocyte response and expression of neurotrophic and inflammatory factors.
Oliveira-Junior MS, Pereira EP, de Amorim VCM, Reis LTC, do Nascimento RP, da Silva VDA, Costa SL. Oliveira-Junior MS, et al. Among authors: da silva vda. Int Immunopharmacol. 2019 May;70:302-312. doi: 10.1016/j.intimp.2019.02.055. Epub 2019 Mar 7. Int Immunopharmacol. 2019. PMID: 30852286 Free article.
The flavonoid rutin and its aglycone quercetin modulate the microglia inflammatory profile improving antiglioma activity.
da Silva AB, Cerqueira Coelho PL, das Neves Oliveira M, Oliveira JL, Oliveira Amparo JA, da Silva KC, Soares JRP, Pitanga BPS, Dos Santos Souza C, de Faria Lopes GP, da Silva VDA, de Fátima Dias Costa M, Junier MP, Chneiweiss H, Moura-Neto V, Costa SL. da Silva AB, et al. Among authors: da silva vda, da silva kc. Brain Behav Immun. 2020 Mar;85:170-185. doi: 10.1016/j.bbi.2019.05.003. Epub 2019 May 3. Brain Behav Immun. 2020. PMID: 31059805
Agathisflavone modulates astrocytic responses and increases the population of neurons in an in vitro model of traumatic brain injury.
de Amorim VCM, Júnior MSO, da Silva AB, David JM, David JPL, de Fátima Dias Costa M, Butt AM, da Silva VDA, Costa SL. de Amorim VCM, et al. Among authors: da silva ab, da silva vda. Naunyn Schmiedebergs Arch Pharmacol. 2020 Oct;393(10):1921-1930. doi: 10.1007/s00210-020-01905-2. Epub 2020 May 22. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 32444988
JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin Expression.
Furtado ABV, Gonçalves DF, Hartmann DD, Courtes AA, Cassol G, Nunez-Figueredo Y, Argolo DS, do Nascimento RP, Costa SL, da Silva VDA, Royes LFF, Soares FAA. Furtado ABV, et al. Among authors: da silva vda. Mol Neurobiol. 2021 Sep;58(9):4615-4627. doi: 10.1007/s12035-021-02436-4. Epub 2021 Jun 19. Mol Neurobiol. 2021. PMID: 34148214
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