Yamamoto N - Search Results

1

Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring.

Iio K, Saitoh T, Ohshita R, Hino T, Amezawa M, Takayama Y, Nagumo Y, Yamamoto N, Kutsumura N, Irukayama-Tomobe Y, Ishikawa Y, Tanimura R, Yanagisawa M, Nagase H. Iio K, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2022 Mar 15;60:128555. doi: 10.1016/j.bmcl.2022.128555. Epub 2022 Jan 17. Bioorg Med Chem Lett. 2022. PMID: 35051577

2

Synthesis of a stable iminium salt and propellane derivatives.

Nagase H, Yamamoto N, Nemoto T, Yoza K, Kamiya K, Hirono S, Momen S, Izumimoto N, Hasebe K, Mochizuki H, Fujii H. Nagase H, et al. Among authors: yamamoto n. J Org Chem. 2008 Oct 17;73(20):8093-6. doi: 10.1021/jo801276z. Epub 2008 Sep 24. J Org Chem. 2008. PMID: 18811203

3

Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration.

Nagase H, Nemoto T, Matsubara A, Saito M, Yamamoto N, Osa Y, Hirayama S, Nakajima M, Nakao K, Mochizuki H, Fujii H. Nagase H, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6302-5. doi: 10.1016/j.bmcl.2010.08.083. Epub 2010 Aug 21. Bioorg Med Chem Lett. 2010. PMID: 20850307

4

Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies.

Nemoto T, Yamamoto N, Watanabe A, Fujii H, Hasebe K, Nakajima M, Mochizuki H, Nagase H. Nemoto T, et al. Among authors: yamamoto n. Bioorg Med Chem. 2011 Feb 1;19(3):1205-21. doi: 10.1016/j.bmc.2010.12.035. Epub 2010 Dec 21. Bioorg Med Chem. 2011. PMID: 21256034

5

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology: part 1.

Yamamoto N, Fujii H, Nemoto T, Nakajima R, Momen S, Izumimoto N, Hasebe K, Mochizuki H, Nagase H. Yamamoto N, et al. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4104-7. doi: 10.1016/j.bmcl.2011.04.147. Epub 2011 May 10. Bioorg Med Chem Lett. 2011. PMID: 21641798

6

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: part 3, novel propellane derivatives with pentacyclic skeletons.

Fujii H, Nakajima R, Akiyama J, Yamamoto N, Hirayama S, Nemoto T, Gouda H, Hirono S, Nagase H. Fujii H, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7697-701. doi: 10.1016/j.bmcl.2012.09.102. Epub 2012 Oct 5. Bioorg Med Chem Lett. 2012. PMID: 23116891

7

The effect of 17-N substituents on the activity of the opioid κ receptor in nalfurafine derivatives.

Nemoto T, Yamamoto N, Wada N, Harada Y, Tomatsu M, Ishihara M, Hirayama S, Iwai T, Fujii H, Nagase H. Nemoto T, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2013 Jan 1;23(1):268-72. doi: 10.1016/j.bmcl.2012.10.100. Epub 2012 Oct 30. Bioorg Med Chem Lett. 2013. PMID: 23200250

8

Design and synthesis of quinolinopropellane derivatives with selective δ opioid receptor agonism.

Nagase H, Nakajima R, Yamamoto N, Hirayama S, Iwai T, Nemoto T, Gouda H, Hirono S, Fujii H. Nagase H, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2851-4. doi: 10.1016/j.bmcl.2014.04.098. Epub 2014 May 4. Bioorg Med Chem Lett. 2014. PMID: 24835200

9

Investigation of 7-benzylidenenaltrexone derivatives as a novel structural antitrichomonal lead compound.

Kutsumura N, Nakajima R, Koyama Y, Miyata Y, Saitoh T, Yamamoto N, Iwata S, Fujii H, Nagase H. Kutsumura N, et al. Among authors: yamamoto n. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4890-4892. doi: 10.1016/j.bmcl.2015.06.002. Epub 2015 Jun 10. Bioorg Med Chem Lett. 2015. PMID: 26099536

10

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain.

Nakajima R, Yamamoto N, Hirayama S, Iwai T, Saitoh A, Nagumo Y, Fujii H, Nagase H. Nakajima R, et al. Among authors: yamamoto n. Bioorg Med Chem. 2015 Oct 1;23(19):6271-9. doi: 10.1016/j.bmc.2015.08.036. Epub 2015 Aug 28. Bioorg Med Chem. 2015. PMID: 26346669

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