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Discovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring.
Iio K, Saitoh T, Ohshita R, Hino T, Amezawa M, Takayama Y, Nagumo Y, Yamamoto N, Kutsumura N, Irukayama-Tomobe Y, Ishikawa Y, Tanimura R, Yanagisawa M, Nagase H. Iio K, et al. Among authors: hino t. Bioorg Med Chem Lett. 2022 Mar 15;60:128555. doi: 10.1016/j.bmcl.2022.128555. Epub 2022 Jan 17. Bioorg Med Chem Lett. 2022. PMID: 35051577
Increased intramuscular adipose tissue of the quadriceps at admission is more strongly related to activities of daily living recovery at discharge compared to muscle mass loss in older patients with aspiration pneumonia.
Akazawa N, Funai K, Hino T, Tsuji R, Tamura W, Tamura K, Hioka A, Moriyama H. Akazawa N, et al. Among authors: hino t. BMC Geriatr. 2024 Jan 29;24(1):107. doi: 10.1186/s12877-024-04718-7. BMC Geriatr. 2024. PMID: 38287269 Free PMC article.
510 results