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Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome.
Panagaki T, Lozano-Montes L, Janickova L, Zuhra K, Szabo MP, Majtan T, Rainer G, Maréchal D, Herault Y, Szabo C. Panagaki T, et al. Among authors: herault y. Redox Biol. 2022 May;51:102233. doi: 10.1016/j.redox.2022.102233. Epub 2022 Jan 13. Redox Biol. 2022. PMID: 35042677 Free PMC article.
The in vivo Down syndrome genomic library in mouse.
Herault Y, Duchon A, Velot E, Maréchal D, Brault V. Herault Y, et al. Prog Brain Res. 2012;197:169-97. doi: 10.1016/B978-0-444-54299-1.00009-1. Prog Brain Res. 2012. PMID: 22541293
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation.
Sartori M, Mendes T, Desai S, Lasorsa A, Herledan A, Malmanche N, Mäkinen P, Marttinen M, Malki I, Chapuis J, Flaig A, Vreulx AC, Ciancia M, Amouyel P, Leroux F, Déprez B, Cantrelle FX, Maréchal D, Pradier L, Hiltunen M, Landrieu I, Kilinc D, Herault Y, Laporte J, Lambert JC. Sartori M, et al. Among authors: herault y. Acta Neuropathol. 2019 Oct;138(4):631-652. doi: 10.1007/s00401-019-02017-9. Epub 2019 May 7. Acta Neuropathol. 2019. PMID: 31065832 Free PMC article.
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.
Lana-Elola E, Aoidi R, Llorian M, Gibbins D, Buechsenschuetz C, Bussi C, Flynn H, Gilmore T, Watson-Scales S, Haugsten Hansen M, Hayward D, Song OR, Brault V, Herault Y, Deau E, Meijer L, Snijders AP, Gutierrez MG, Fisher EMC, Tybulewicz VLJ. Lana-Elola E, et al. Among authors: herault y. Sci Transl Med. 2024 Jan 24;16(731):eadd6883. doi: 10.1126/scitranslmed.add6883. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266108 Free PMC article.
203 results