Hanrahan JW - Search Results

1

Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A.

Lopes-Pacheco M, Bacalhau M, Ramalho SS, Silva IAL, Ferreira FC, Carlile GW, Thomas DY, Farinha CM, Hanrahan JW, Amaral MD. Lopes-Pacheco M, et al. Among authors: hanrahan jw. Cells. 2022 Jan 1;11(1):136. doi: 10.3390/cells11010136. Cells. 2022. PMID: 35011698 Free PMC article.

2

Glutathione permeability of CFTR.

Linsdell P, Hanrahan JW. Linsdell P, et al. Among authors: hanrahan jw. Am J Physiol. 1998 Jul;275(1):C323-6. doi: 10.1152/ajpcell.1998.275.1.C323. Am J Physiol. 1998. PMID: 9688865

3

Phosphorylation of CFTR by PKA promotes binding of the regulatory domain.

Chappe V, Irvine T, Liao J, Evagelidis A, Hanrahan JW. Chappe V, et al. Among authors: hanrahan jw. EMBO J. 2005 Aug 3;24(15):2730-40. doi: 10.1038/sj.emboj.7600747. Epub 2005 Jul 7. EMBO J. 2005. PMID: 16001079 Free PMC article.

4

Correctors of protein trafficking defects identified by a novel high-throughput screening assay.

Carlile GW, Robert R, Zhang D, Teske KA, Luo Y, Hanrahan JW, Thomas DY. Carlile GW, et al. Among authors: hanrahan jw. Chembiochem. 2007 Jun 18;8(9):1012-20. doi: 10.1002/cbic.200700027. Chembiochem. 2007. PMID: 17497613

5

Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect.

Robert R, Carlile GW, Pavel C, Liu N, Anjos SM, Liao J, Luo Y, Zhang D, Thomas DY, Hanrahan JW. Robert R, et al. Among authors: hanrahan jw. Mol Pharmacol. 2008 Feb;73(2):478-89. doi: 10.1124/mol.107.040725. Epub 2007 Nov 1. Mol Pharmacol. 2008. PMID: 17975008

6

BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex.

Wang B, Heath-Engel H, Zhang D, Nguyen N, Thomas DY, Hanrahan JW, Shore GC. Wang B, et al. Among authors: hanrahan jw. Cell. 2008 Jun 13;133(6):1080-92. doi: 10.1016/j.cell.2008.04.042. Cell. 2008. PMID: 18555783 Free article.

7

Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine.

Robert R, Carlile GW, Liao J, Balghi H, Lesimple P, Liu N, Kus B, Rotin D, Wilke M, de Jonge HR, Scholte BJ, Thomas DY, Hanrahan JW. Robert R, et al. Among authors: hanrahan jw. Mol Pharmacol. 2010 Jun;77(6):922-30. doi: 10.1124/mol.109.062679. Epub 2010 Mar 3. Mol Pharmacol. 2010. PMID: 20200141

8

Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR.

Sampson HM, Robert R, Liao J, Matthes E, Carlile GW, Hanrahan JW, Thomas DY. Sampson HM, et al. Among authors: hanrahan jw. Chem Biol. 2011 Feb 25;18(2):231-42. doi: 10.1016/j.chembiol.2010.11.016. Chem Biol. 2011. PMID: 21338920

9

Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways.

Balghi H, Robert R, Rappaz B, Zhang X, Wohlhuter-Haddad A, Evagelidis A, Luo Y, Goepp J, Ferraro P, Roméo P, Trebak M, Wiseman PW, Thomas DY, Hanrahan JW. Balghi H, et al. Among authors: hanrahan jw. FASEB J. 2011 Dec;25(12):4274-91. doi: 10.1096/fj.11-187682. Epub 2011 Aug 26. FASEB J. 2011. PMID: 21873556 Free PMC article.

10

Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking.

Anjos SM, Robert R, Waller D, Zhang DL, Balghi H, Sampson HM, Ciciriello F, Lesimple P, Carlile GW, Goepp J, Liao J, Ferraro P, Phillipe R, Dantzer F, Hanrahan JW, Thomas DY. Anjos SM, et al. Among authors: hanrahan jw. Front Pharmacol. 2012 Sep 12;3:165. doi: 10.3389/fphar.2012.00165. eCollection 2012. Front Pharmacol. 2012. PMID: 22988441 Free PMC article.

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