Rast G - Search Results

1

Ion Channel Expression and Electrophysiology of Singular Human (Primary and Induced Pluripotent Stem Cell-Derived) Cardiomyocytes.

Schmid C, Abi-Gerges N, Leitner MG, Zellner D, Rast G. Schmid C, et al. Among authors: rast g. Cells. 2021 Nov 30;10(12):3370. doi: 10.3390/cells10123370. Cells. 2021. PMID: 34943878 Free PMC article.

2

Characterization of iCell cardiomyocytes using single-cell RNA-sequencing methods.

Schmid C, Wohnhaas CT, Hildebrandt T, Baum P, Rast G. Schmid C, et al. Among authors: rast g. J Pharmacol Toxicol Methods. 2020 Nov-Dec;106:106915. doi: 10.1016/j.vascn.2020.106915. Epub 2020 Aug 29. J Pharmacol Toxicol Methods. 2020. PMID: 32871229 Free article.

3

Comparison of in vitro and computational experiments on the relation of inter-beat interval and duration of repolarization in a specific type of human induced pluripotent stem cell-derived cardiomyocytes.

Kügler P, Rast G, Guth BD. Kügler P, et al. Among authors: rast g. PLoS One. 2019 Sep 9;14(9):e0221763. doi: 10.1371/journal.pone.0221763. eCollection 2019. PLoS One. 2019. PMID: 31498812 Free PMC article.

4

Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection.

Rast G, Kraushaar U, Buckenmaier S, Ittrich C, Guth BD. Rast G, et al. J Pharmacol Toxicol Methods. 2016 Nov-Dec;82:74-82. doi: 10.1016/j.vascn.2016.08.002. Epub 2016 Aug 9. J Pharmacol Toxicol Methods. 2016. PMID: 27521052

5

An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes.

Rast G, Weber J, Disch C, Schuck E, Ittrich C, Guth BD. Rast G, et al. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:91-100. doi: 10.1016/j.vascn.2015.04.005. Epub 2015 Apr 25. J Pharmacol Toxicol Methods. 2015. PMID: 25921432

6

Solubility assessment and on-line exposure confirmation in a patch-clamp assay for hERG (human ether-a-go-go-related gene) potassium channel inhibition.

Rast G, Guth BD. Rast G, et al. J Pharmacol Toxicol Methods. 2014 Sep-Oct;70(2):182-7. doi: 10.1016/j.vascn.2014.08.001. Epub 2014 Aug 10. J Pharmacol Toxicol Methods. 2014. PMID: 25117629

7

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.

Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM. Just S, et al. Among authors: rast g. PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018. PLoS One. 2018. PMID: 29385160 Free PMC article.

8

Dealing with hERG liabilities early: diverse approaches to an important goal in drug development.

Guth BD, Rast G. Guth BD, et al. Among authors: rast g. Br J Pharmacol. 2010 Jan;159(1):22-4. doi: 10.1111/j.1476-5381.2009.00265.x. Br J Pharmacol. 2010. PMID: 20141517 Free PMC article.

9

A multi-slice recording system for stable late phase hippocampal long-term potentiation experiments.

Kroker KS, Rosenbrock H, Rast G. Kroker KS, et al. Among authors: rast g. J Neurosci Methods. 2011 Jan 15;194(2):394-401. doi: 10.1016/j.jneumeth.2010.11.006. Epub 2010 Nov 16. J Neurosci Methods. 2011. PMID: 21087635

10

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.

Lin BL, Matera D, Doerner JF, Zheng N, Del Camino D, Mishra S, Bian H, Zeveleva S, Zhen X, Blair NT, Chong JA, Hessler DP, Bedja D, Zhu G, Muller GK, Ranek MJ, Pantages L, McFarland M, Netherton MR, Berry A, Wong D, Rast G, Qian HS, Weldon SM, Kuo JJ, Sauer A, Sarko C, Moran MM, Kass DA, Pullen SS. Lin BL, et al. Among authors: rast g. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161. doi: 10.1073/pnas.1815354116. Epub 2019 Apr 26. Proc Natl Acad Sci U S A. 2019. PMID: 31028142 Free PMC article.

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