Kalra P - Search Results

1

Dihydropyridine Lactam Analogs Targeting BET Bromodomains.

Jiang J, Sigua LH, Chan A, Kalra P, Pomerantz WCK, Schönbrunn E, Qi J, Georg GI. Jiang J, et al. Among authors: kalra p. ChemMedChem. 2022 Jan 5;17(1):e202100407. doi: 10.1002/cmdc.202100407. Epub 2021 Dec 21. ChemMedChem. 2022. PMID: 34932262 Free PMC article.

2

NMR Analyses of Acetylated H2A.Z Isoforms Identify Differential Binding Interactions with the Bromodomain of the NURF Nucleosome Remodeling Complex.

Olson NM, Kroc S, Johnson JA, Zahid H, Ycas PD, Chan A, Kimbrough JR, Kalra P, Schönbrunn E, Pomerantz WCK. Olson NM, et al. Among authors: kalra p. Biochemistry. 2020 May 26;59(20):1871-1880. doi: 10.1021/acs.biochem.0c00159. Epub 2020 May 11. Biochemistry. 2020. PMID: 32356653 Free PMC article.

3

Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins.

Kalra P, McGraw L, Kimbrough JR, Pandey AK, Solberg J, Cui H, Divakaran A, John K, Hawkinson JE, Pomerantz WCK. Kalra P, et al. ACS Chem Biol. 2020 Nov 20;15(11):3038-3049. doi: 10.1021/acschembio.0c00720. Epub 2020 Nov 3. ACS Chem Biol. 2020. PMID: 33138352 Free PMC article.

4

Alternative Mechanisms for DNA Engagement by BET Bromodomain-Containing Proteins.

Kalra P, Zahid H, Ayoub A, Dou Y, Pomerantz WCK. Kalra P, et al. Biochemistry. 2022 Jul 5;61(13):1260-1272. doi: 10.1021/acs.biochem.2c00157. Epub 2022 Jun 24. Biochemistry. 2022. PMID: 35748495 Free PMC article.

5

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Brand M, Clayton J, Moroglu M, Schiedel M, Picaud S, Bluck JP, Skwarska A, Bolland H, Chan AKN, Laurin CMC, Scorah AR, See L, Rooney TPC, Andrews KH, Fedorov O, Perell G, Kalra P, Vinh KB, Cortopassi WA, Heitel P, Christensen KE, Cooper RI, Paton RS, Pomerantz WCK, Biggin PC, Hammond EM, Filippakopoulos P, Conway SJ. Brand M, et al. Among authors: kalra p. J Med Chem. 2021 Jul 22;64(14):10102-10123. doi: 10.1021/acs.jmedchem.1c00348. Epub 2021 Jul 13. J Med Chem. 2021. PMID: 34255515 Free PMC article.

6

Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors.

Braun AR, Liao EE, Horvath M, Kalra P, Acosta K, Young MC, Kochen NN, Lo CH, Brown R, Evans MD, Pomerantz WCK, Rhoades E, Luk K, Cornea RL, Thomas DD, Sachs JN. Braun AR, et al. Among authors: kalra p. NPJ Parkinsons Dis. 2021 Jun 28;7(1):52. doi: 10.1038/s41531-021-00195-6. NPJ Parkinsons Dis. 2021. PMID: 34183676 Free PMC article.

7

Free energy component analysis for drug design: a case study of HIV-1 protease-inhibitor binding.

Kalra P, Reddy TV, Jayaram B. Kalra P, et al. J Med Chem. 2001 Dec 6;44(25):4325-38. doi: 10.1021/jm010175z. J Med Chem. 2001. PMID: 11728180

8

A molecular dynamics study based post facto free energy analysis of the binding of bovine angiogenin with UMP and CMP ligands.

Madhusudhan MS, Vishveshwara S, Das A, Kalra P, Jayaram B. Madhusudhan MS, et al. Among authors: kalra p. Indian J Biochem Biophys. 2001 Feb-Apr;38(1-2):27-33. Indian J Biochem Biophys. 2001. PMID: 11563327

9

Free-energy analysis of enzyme-inhibitor binding: aspartic proteinase-pepstatin complexes.

Kalra P, Das A, Jayaram B. Kalra P, et al. Appl Biochem Biotechnol. 2001 Oct-Dec;96(1-3):93-108. doi: 10.1385/abab:96:1-3:093. Appl Biochem Biotechnol. 2001. PMID: 11783905

10

Post-Transplant Cardiovascular Disease in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes in the Era of Modern Immunosuppression.

Chukwu CA, Rao A, Middleton R, Kalra PA. Chukwu CA, et al. Among authors: kalra pa. J Clin Med. 2024 May 7;13(10):2734. doi: 10.3390/jcm13102734. J Clin Med. 2024. PMID: 38792274 Free PMC article.

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