Tawfik DS - Search Results

1

A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis.

Jayaraman V, Lee DJ, Elad N, Vimer S, Sharon M, Fraser JS, Tawfik DS. Jayaraman V, et al. Among authors: tawfik ds. Nat Chem Biol. 2022 Feb;18(2):161-170. doi: 10.1038/s41589-021-00919-y. Epub 2021 Dec 20. Nat Chem Biol. 2022. PMID: 34931064 Free PMC article.

2

Chaperonin overexpression promotes genetic variation and enzyme evolution.

Tokuriki N, Tawfik DS. Tokuriki N, et al. Among authors: tawfik ds. Nature. 2009 Jun 4;459(7247):668-73. doi: 10.1038/nature08009. Nature. 2009. PMID: 19494908

3

Metamorphic proteins mediate evolutionary transitions of structure.

Yadid I, Kirshenbaum N, Sharon M, Dym O, Tawfik DS. Yadid I, et al. Among authors: tawfik ds. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7287-92. doi: 10.1073/pnas.0912616107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368465 Free PMC article.

4

Messy biology and the origins of evolutionary innovations.

Tawfik DS. Tawfik DS. Nat Chem Biol. 2010 Oct;6(10):692-6. doi: 10.1038/nchembio.441. Nat Chem Biol. 2010. PMID: 20852602

5

Negative Epistasis and Evolvability in TEM-1 β-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder.

Dellus-Gur E, Elias M, Caselli E, Prati F, Salverda ML, de Visser JA, Fraser JS, Tawfik DS. Dellus-Gur E, et al. Among authors: tawfik ds. J Mol Biol. 2015 Jul 17;427(14):2396-409. doi: 10.1016/j.jmb.2015.05.011. Epub 2015 May 22. J Mol Biol. 2015. PMID: 26004540 Free PMC article.

6

The Evolutionary Potential of Phenotypic Mutations.

Yanagida H, Gispan A, Kadouri N, Rozen S, Sharon M, Barkai N, Tawfik DS. Yanagida H, et al. Among authors: tawfik ds. PLoS Genet. 2015 Aug 5;11(8):e1005445. doi: 10.1371/journal.pgen.1005445. eCollection 2015 Aug. PLoS Genet. 2015. PMID: 26244544 Free PMC article.

7

Native Mass Spectrometry of Recombinant Proteins from Crude Cell Lysates.

Gan J, Ben-Nissan G, Arkind G, Tarnavsky M, Trudeau D, Noda Garcia L, Tawfik DS, Sharon M. Gan J, et al. Among authors: tawfik ds. Anal Chem. 2017 Apr 18;89(8):4398-4404. doi: 10.1021/acs.analchem.7b00398. Epub 2017 Apr 5. Anal Chem. 2017. PMID: 28345863 Free PMC article.

8

Bacilli glutamate dehydrogenases diverged via coevolution of transcription and enzyme regulation.

Noda-Garcia L, Romero Romero ML, Longo LM, Kolodkin-Gal I, Tawfik DS. Noda-Garcia L, et al. Among authors: tawfik ds. EMBO Rep. 2017 Jul;18(7):1139-1149. doi: 10.15252/embr.201743990. Epub 2017 May 3. EMBO Rep. 2017. PMID: 28468957 Free PMC article.

9

Rescue of conformational dynamics in enzyme catalysis by directed evolution.

Otten R, Liu L, Kenner LR, Clarkson MW, Mavor D, Tawfik DS, Kern D, Fraser JS. Otten R, et al. Among authors: tawfik ds. Nat Commun. 2018 Apr 3;9(1):1314. doi: 10.1038/s41467-018-03562-9. Nat Commun. 2018. PMID: 29615624 Free PMC article.

10

Simple yet functional phosphate-loop proteins.

Romero Romero ML, Yang F, Lin YR, Toth-Petroczy A, Berezovsky IN, Goncearenco A, Yang W, Wellner A, Kumar-Deshmukh F, Sharon M, Baker D, Varani G, Tawfik DS. Romero Romero ML, et al. Among authors: tawfik ds. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11943-E11950. doi: 10.1073/pnas.1812400115. Epub 2018 Nov 30. Proc Natl Acad Sci U S A. 2018. PMID: 30504143 Free PMC article.

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