Lieu YK - Search Results

1

SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes.

Lieu YK, Liu Z, Ali AM, Wei X, Penson A, Zhang J, An X, Rabadan R, Raza A, Manley JL, Mukherjee S. Lieu YK, et al. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2111703119. doi: 10.1073/pnas.2111703119. Proc Natl Acad Sci U S A. 2022. PMID: 34930825 Free PMC article.

2

Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities.

Zhang J, Lieu YK, Ali AM, Penson A, Reggio KS, Rabadan R, Raza A, Mukherjee S, Manley JL. Zhang J, et al. Among authors: lieu yk. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4726-34. doi: 10.1073/pnas.1514105112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261309 Free PMC article.

3

Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.

Zhang J, Ali AM, Lieu YK, Liu Z, Gao J, Rabadan R, Raza A, Mukherjee S, Manley JL. Zhang J, et al. Among authors: lieu yk. Mol Cell. 2019 Oct 3;76(1):82-95.e7. doi: 10.1016/j.molcel.2019.07.017. Epub 2019 Aug 29. Mol Cell. 2019. PMID: 31474574 Free PMC article.

4

Dnmt3a regulates myeloproliferation and liver-specific expansion of hematopoietic stem and progenitor cells.

Guryanova OA, Lieu YK, Garrett-Bakelman FE, Spitzer B, Glass JL, Shank K, Martinez AB, Rivera SA, Durham BH, Rapaport F, Keller MD, Pandey S, Bastian L, Tovbin D, Weinstein AR, Teruya-Feldstein J, Abdel-Wahab O, Santini V, Mason CE, Melnick AM, Mukherjee S, Levine RL. Guryanova OA, et al. Among authors: lieu yk. Leukemia. 2016 May;30(5):1133-42. doi: 10.1038/leu.2015.358. Epub 2015 Dec 29. Leukemia. 2016. PMID: 26710888 Free PMC article.

5

Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation.

Lieu YK, Reddy EP. Lieu YK, et al. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21689-94. doi: 10.1073/pnas.0907623106. Epub 2009 Dec 2. Proc Natl Acad Sci U S A. 2009. PMID: 19955420 Free PMC article.

6

B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development.

Baker SJ, Ma'ayan A, Lieu YK, John P, Reddy MV, Chen EY, Duan Q, Snoeck HW, Reddy EP. Baker SJ, et al. Among authors: lieu yk. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3122-7. doi: 10.1073/pnas.1315464111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516162 Free PMC article.

7

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.

Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G, Rivera SA, Chramiec AG, Pronier E, Bastian L, Keller MD, Tovbin D, Loizou E, Weinstein AR, Gonzalez AR, Lieu YK, Rowe JM, Pastore F, McKenney AS, Krivtsov AV, Sperr WR, Cross JR, Mason CE, Tallman MS, Arcila ME, Abdel-Wahab O, Armstrong SA, Kubicek S, Staber PB, Gönen M, Paietta EM, Melnick AM, Nimer SD, Mukherjee S, Levine RL. Guryanova OA, et al. Among authors: lieu yk. Nat Med. 2016 Dec;22(12):1488-1495. doi: 10.1038/nm.4210. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841873 Free PMC article.

8

Requirement of c-myb in T cell development and in mature T cell function.

Lieu YK, Kumar A, Pajerowski AG, Rogers TJ, Reddy EP. Lieu YK, et al. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14853-8. doi: 10.1073/pnas.0405338101. Epub 2004 Oct 4. Proc Natl Acad Sci U S A. 2004. PMID: 15466706 Free PMC article.

9

Impaired adult myeloid progenitor CMP and GMP cell function in conditional c-myb-knockout mice.

Lieu YK, Reddy EP. Lieu YK, et al. Cell Cycle. 2012 Sep 15;11(18):3504-12. doi: 10.4161/cc.21802. Epub 2012 Aug 23. Cell Cycle. 2012. PMID: 22918254 Free PMC article.

10

Combined genetic inactivation of β2-Microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma.

Challa-Malladi M, Lieu YK, Califano O, Holmes AB, Bhagat G, Murty VV, Dominguez-Sola D, Pasqualucci L, Dalla-Favera R. Challa-Malladi M, et al. Among authors: lieu yk. Cancer Cell. 2011 Dec 13;20(6):728-40. doi: 10.1016/j.ccr.2011.11.006. Epub 2011 Dec 1. Cancer Cell. 2011. PMID: 22137796 Free PMC article.

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