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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: singh h. Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 2. Cell Rep Med. 2021. PMID: 34873589 Free PMC article.
Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche.
Hirai T, Yang Y, Zenke Y, Li H, Chaudhri VK, De La Cruz Diaz JS, Zhou PY, Nguyen BA, Bartholin L, Workman CJ, Griggs DW, Vignali DAA, Singh H, Masopust D, Kaplan DH. Hirai T, et al. Among authors: singh h. Immunity. 2021 Jan 12;54(1):84-98.e5. doi: 10.1016/j.immuni.2020.10.022. Epub 2020 Nov 18. Immunity. 2021. PMID: 33212014 Free PMC article.
Bifurcated monocyte states are predictive of mortality in severe COVID-19.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: singh h. bioRxiv [Preprint]. 2021 Feb 10:2021.02.10.430499. doi: 10.1101/2021.02.10.430499. bioRxiv. 2021. PMID: 33594364 Free PMC article. Preprint.
Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19.
Peddireddy SP, Rahman SA, Cillo AR, Vijay GM, Somasundaram A, Workman CJ, Bain W, McVerry BJ, Methe B, Lee JS, Ray P, Ray A, Bruno TC, Vignali DAA, Kitsios GD, Morris A, Singh H, Sarkar A, Das J. Peddireddy SP, et al. Among authors: singh h. Cell Rep. 2022 Jun 28;39(13):111020. doi: 10.1016/j.celrep.2022.111020. Epub 2022 Jun 13. Cell Rep. 2022. PMID: 35738278 Free PMC article.
Temporal dynamics and genomic programming of plasma cell fates.
Manakkat Vijay GK, Zhou M, Thakkar K, Rothrauff A, Chawla AS, Chen D, Lau LC, Gerges PH, Chetal K, Chhibbar P, Fan J, Das J, Joglekar A, Borghesi L, Salomonis N, Xu H, Singh H. Manakkat Vijay GK, et al. Among authors: singh h. Nat Immunol. 2024 May 2. doi: 10.1038/s41590-024-01831-y. Online ahead of print. Nat Immunol. 2024. PMID: 38698087
DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data.
DePasquale EAK, Schnell DJ, Van Camp PJ, Valiente-Alandí Í, Blaxall BC, Grimes HL, Singh H, Salomonis N. DePasquale EAK, et al. Among authors: singh h. Cell Rep. 2019 Nov 5;29(6):1718-1727.e8. doi: 10.1016/j.celrep.2019.09.082. Cell Rep. 2019. PMID: 31693907 Free PMC article.
Temporal dynamics and genomic programming of plasma cell fates.
Vijay GKM, Zhou M, Thakkar K, Rothrauff A, Chawla AS, Chen D, Lau LC, Habib P, Chetal K, Chhibbar P, Fan J, Das J, Joglekar A, Borghesi L, Salomonis N, Xu H, Singh H. Vijay GKM, et al. Among authors: singh h. Res Sq [Preprint]. 2023 Sep 6:rs.3.rs-3296446. doi: 10.21203/rs.3.rs-3296446/v1. Res Sq. 2023. PMID: 37720050 Free PMC article. Updated. Preprint.
7,298 results