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Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes.
Jain R, Özgümüş T, Jensen TM, du Plessis E, Keindl M, Møller CL, Falhammar H, Nyström T, Catrina SB, Jörneskog G, Jessen LE, Forsblom C, Haukka JK, Groop PH, Rossing P, Groop L, Eliasson M, Eliasson B, Brismar K, Al-Majdoub M, Nilsson PM, Taskinen MR, Ferrannini E, Spégel P, Berg TJ, Lyssenko V. Jain R, et al. Sci Rep. 2020 Jul 14;10(1):11561. doi: 10.1038/s41598-020-68130-y. Sci Rep. 2020. PMID: 32665614 Free PMC article.
Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms.
Keindl M, Fedotkina O, du Plessis E, Jain R, Bergum B, Mygind Jensen T, Laustrup Møller C, Falhammar H, Nyström T, Catrina SB, Jörneskog G, Groop L, Eliasson M, Eliasson B, Brismar K, Nilsson PM, Berg TJ, Appel S, Lyssenko V. Keindl M, et al. Among authors: jain r. Front Endocrinol (Lausanne). 2020 Oct 30;11:575469. doi: 10.3389/fendo.2020.575469. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33193091 Free PMC article.
Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes.
Fedotkina O, Luk A, Jain R, Prasad RB, Shungin D, Simó-Servat O, Özgümüs T, Cherviakova L, Khalimon N, Svietleisha T, Buldenko T, Kravchenko V, Hernández C, Jain D, Simo R, Artner I, Nilsson PM, Khalangot MD, Vaiserman AM, Chan J, Vaag A, Lyssenko V. Fedotkina O, et al. Among authors: jain r, jain d. Acta Ophthalmol. 2022 Mar;100(2):e539-e545. doi: 10.1111/aos.14948. Epub 2021 Jun 24. Acta Ophthalmol. 2022. PMID: 34169655 Free article.
Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study.
Özgümüş T, Sulaieva O, Jessen LE, Jain R, Falhammar H, Nyström T, Catrina SB, Jörneskog G, Groop L, Eliasson M, Eliasson B, Brismar K, Stokowy T, Nilsson PM, Lyssenko V. Özgümüş T, et al. Among authors: jain r. Sci Rep. 2021 Oct 20;11(1):20735. doi: 10.1038/s41598-021-00183-z. Sci Rep. 2021. PMID: 34671071 Free PMC article.
Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes.
Fedotkina O, Jain R, Prasad RB, Luk A, García-Ramírez M, Özgümüs T, Cherviakova L, Khalimon N, Svietleisha T, Buldenko T, Kravchenko V, Jain D, Vaag A, Chan J, Khalangot MD, Hernández C, Nilsson PM, Simo R, Artner I, Lyssenko V. Fedotkina O, et al. Among authors: jain r, jain d. Front Neurosci. 2022 May 5;16:858049. doi: 10.3389/fnins.2022.858049. eCollection 2022. Front Neurosci. 2022. PMID: 35600617 Free PMC article.
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
Schriever SC, Kabra DG, Pfuhlmann K, Baumann P, Baumgart EV, Nagler J, Seebacher F, Harrison L, Irmler M, Kullmann S, Corrêa-da-Silva F, Giesert F, Jain R, Schug H, Castel J, Martinez S, Wu M, Häring HU, de Angelis MH, Beckers J, Müller TD, Stemmer K, Wurst W, Rozman J, Nogueiras R, De Angelis M, Molkentin JD, Krahmer N, Yi CX, Schmidt MV, Luquet S, Heni M, Tschöp MH, Pfluger PT. Schriever SC, et al. Among authors: jain r. J Clin Invest. 2020 Nov 2;130(11):6093-6108. doi: 10.1172/JCI136363. J Clin Invest. 2020. PMID: 32780722 Free PMC article.
Lenvatinib Plus Pembrolizumab Versus Standard of Care for Previously Treated Metastatic Colorectal Cancer: Final Analysis of the Randomized, Open-Label, Phase III LEAP-017 Study.
Kawazoe A, Xu RH, García-Alfonso P, Passhak M, Teng HW, Shergill A, Gumus M, Qvortrup C, Stintzing S, Towns K, Kim TW, Shiu KK, Cundom J, Ananda S, Lebedinets A, Fu R, Jain R, Adelberg D, Heinemann V, Yoshino T, Elez E; LEAP-017 Investigators. Kawazoe A, et al. Among authors: jain r. J Clin Oncol. 2024 Jun 4:JCO2302736. doi: 10.1200/JCO.23.02736. Online ahead of print. J Clin Oncol. 2024. PMID: 38833658
5,313 results