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Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin.
Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. Ma J, et al. Among authors: castven d. Int J Cancer. 2020 Nov 1;147(9):2564-2577. doi: 10.1002/ijc.33144. Epub 2020 Jun 23. Int J Cancer. 2020. PMID: 32525563 Free article.
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis.
Czauderna C, Poplawski A, O'Rourke CJ, Castven D, Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W, Schmiel M, Drebber U, Binder H, Ridder DA, Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS, Park YN, Marquardt JU. Czauderna C, et al. Among authors: castven d. JCI Insight. 2021 Sep 8;6(17):e146196. doi: 10.1172/jci.insight.146196. JCI Insight. 2021. PMID: 34375307 Free PMC article.
Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors.
Schmidtlein PM, Volz C, Hackel A, Thürling I, Castven D, Braun R, Wellner UF, Konukiewitz B, Riemekasten G, Lehnert H, Marquardt JU, Ungefroren H. Schmidtlein PM, et al. Among authors: castven d. Cancers (Basel). 2021 Nov 4;13(21):5541. doi: 10.3390/cancers13215541. Cancers (Basel). 2021. PMID: 34771704 Free PMC article.
Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes-Associated Protein 1 Activation and Transient Expansion of Stem-Like Cancer Cells.
Castven D, Czauderna C, Becker D, Pereira S, Schmitt J, Weinmann A, Shah V, Hajduk J, Keggenhoff F, Binder H, Keck T, Heilmann-Heimbach S, Wörns MA, Thorgeirsson SS, Breuhahn K, Galle PR, Marquardt JU. Castven D, et al. Hepatol Commun. 2022 May;6(5):1140-1156. doi: 10.1002/hep4.1869. Epub 2021 Nov 24. Hepatol Commun. 2022. PMID: 34817932 Free PMC article.
The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1-A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting.
Ungefroren H, Thürling I, Färber B, Kowalke T, Fischer T, De Assis LVM, Braun R, Castven D, Oster H, Konukiewitz B, Wellner UF, Lehnert H, Marquardt JU. Ungefroren H, et al. Among authors: castven d. Cancers (Basel). 2022 Apr 19;14(9):2057. doi: 10.3390/cancers14092057. Cancers (Basel). 2022. PMID: 35565186 Free PMC article.
Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer.
Marquardt JU, Gomez-Quiroz L, Arreguin Camacho LO, Pinna F, Lee YH, Kitade M, Domínguez MP, Castven D, Breuhahn K, Conner EA, Galle PR, Andersen JB, Factor VM, Thorgeirsson SS. Marquardt JU, et al. Among authors: castven d. J Hepatol. 2015 Sep;63(3):661-9. doi: 10.1016/j.jhep.2015.04.018. Epub 2015 May 1. J Hepatol. 2015. PMID: 25937435 Free PMC article.
Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas.
Castven D, Fischer M, Becker D, Heinrich S, Andersen JB, Strand D, Sprinzl MF, Strand S, Czauderna C, Heilmann-Heimbach S, Roessler S, Weinmann A, Wörns MA, Thorgeirsson SS, Galle PR, Matter MS, Lang H, Marquardt JU. Castven D, et al. Oncotarget. 2017 Jul 25;8(30):48688-48700. doi: 10.18632/oncotarget.16231. Oncotarget. 2017. PMID: 28415775 Free PMC article.
21 results