Fraaije M - Search Results

1

Whole-cell screening of oxidative enzymes using genetically encoded sensors.

Kardashliev T, Weingartner A, Romero E, Schwaneberg U, Fraaije M, Panke S, Held M. Kardashliev T, et al. Among authors: fraaije m. Chem Sci. 2021 Oct 29;12(44):14766-14772. doi: 10.1039/d1sc02578c. eCollection 2021 Nov 17. Chem Sci. 2021. PMID: 34820092 Free PMC article.

2

Extending the substrate scope of a Baeyer-Villiger monooxygenase by multiple-site mutagenesis.

Dudek HM, Fink MJ, Shivange AV, Dennig A, Mihovilovic MD, Schwaneberg U, Fraaije MW. Dudek HM, et al. Among authors: fraaije mw. Appl Microbiol Biotechnol. 2014 May;98(9):4009-20. doi: 10.1007/s00253-013-5364-1. Epub 2013 Nov 19. Appl Microbiol Biotechnol. 2014. PMID: 24247989

3

Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase.

Romero E, Castellanos JR, Mattevi A, Fraaije MW. Romero E, et al. Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15852-15855. doi: 10.1002/anie.201608951. Epub 2016 Nov 22. Angew Chem Int Ed Engl. 2016. PMID: 27873437 Free PMC article.

4

Engineering Cyclohexanone Monooxygenase for the Production of Methyl Propanoate.

van Beek HL, Romero E, Fraaije MW. van Beek HL, et al. ACS Chem Biol. 2017 Jan 20;12(1):291-299. doi: 10.1021/acschembio.6b00965. Epub 2016 Dec 20. ACS Chem Biol. 2017. PMID: 27935281

5

Crystal structures and atomic model of NADPH oxidase.

Magnani F, Nenci S, Millana Fananas E, Ceccon M, Romero E, Fraaije MW, Mattevi A. Magnani F, et al. Among authors: fraaije mw. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6764-6769. doi: 10.1073/pnas.1702293114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607049 Free PMC article.

6

Two tyrosine residues, Tyr-108 and Tyr-503, are responsible for the deprotonation of phenolic substrates in vanillyl-alcohol oxidase.

Ewing TA, Nguyen QT, Allan RC, Gygli G, Romero E, Binda C, Fraaije MW, Mattevi A, van Berkel WJH. Ewing TA, et al. J Biol Chem. 2017 Sep 1;292(35):14668-14679. doi: 10.1074/jbc.M117.778449. Epub 2017 Jul 17. J Biol Chem. 2017. PMID: 28717004 Free PMC article.

7

Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism.

Fiorentini F, Romero E, Fraaije MW, Faber K, Hall M, Mattevi A. Fiorentini F, et al. Among authors: fraaije mw. ACS Chem Biol. 2017 Sep 15;12(9):2379-2387. doi: 10.1021/acschembio.7b00470. Epub 2017 Aug 21. ACS Chem Biol. 2017. PMID: 28783300

8

Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase.

Burgener S, Schwander T, Romero E, Fraaije MW, Erb TJ. Burgener S, et al. Molecules. 2017 Dec 28;23(1):68. doi: 10.3390/molecules23010068. Molecules. 2017. PMID: 29283425 Free PMC article.

9

Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes.

Romero E, Gómez Castellanos JR, Gadda G, Fraaije MW, Mattevi A. Romero E, et al. Chem Rev. 2018 Feb 28;118(4):1742-1769. doi: 10.1021/acs.chemrev.7b00650. Epub 2018 Jan 11. Chem Rev. 2018. PMID: 29323892

10

Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase.

Pickl M, Swoboda A, Romero E, Winkler CK, Binda C, Mattevi A, Faber K, Fraaije MW. Pickl M, et al. Among authors: fraaije mw. Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2864-2868. doi: 10.1002/anie.201713189. Epub 2018 Feb 15. Angew Chem Int Ed Engl. 2018. PMID: 29384246

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