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Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.
Ewing AD, Houlahan KE, Hu Y, Ellrott K, Caloian C, Yamaguchi TN, Bare JC, P'ng C, Waggott D, Sabelnykova VY; ICGC-TCGA DREAM Somatic Mutation Calling Challenge participants; Kellen MR, Norman TC, Haussler D, Friend SH, Stolovitzky G, Margolin AA, Stuart JM, Boutros PC. Ewing AD, et al. Nat Methods. 2015 Jul;12(7):623-30. doi: 10.1038/nmeth.3407. Epub 2015 May 18. Nat Methods. 2015. PMID: 25984700 Free PMC article.
TNF plays a crucial role in inflammation by signaling via T cell TNFR2.
Alam MS, Otsuka S, Wong N, Abbasi A, Gaida MM, Fan Y, Meerzaman D, Ashwell JD. Alam MS, et al. Among authors: fan y. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2109972118. doi: 10.1073/pnas.2109972118. Proc Natl Acad Sci U S A. 2021. PMID: 34873037 Free PMC article.
Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome.
Thomas D, Palczewski M, Kuschman H, Hoffman B, Yang H, Glynn S, Wilson D, Kool E, Montfort W, Chang J, Petenkaya A, Chronis C, Cundari T, Sappa S, Islam K, McVicar D, Fan Y, Chen Q, Meerzaman D, Sierk M. Thomas D, et al. Among authors: fan y. Res Sq [Preprint]. 2024 Apr 3:rs.3.rs-4131804. doi: 10.21203/rs.3.rs-4131804/v1. Res Sq. 2024. PMID: 38645113 Free PMC article. Preprint.
Neutral tumor evolution?
Tarabichi M, Martincorena I, Gerstung M, Leroi AM, Markowetz F; PCAWG Evolution and Heterogeneity Working Group; Spellman PT, Morris QD, Lingjærde OC, Wedge DC, Van Loo P. Tarabichi M, et al. Nat Genet. 2018 Dec;50(12):1630-1633. doi: 10.1038/s41588-018-0258-x. Nat Genet. 2018. PMID: 30374075 Free PMC article. No abstract available.
18,506 results
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