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Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection.
Lan Q, Pu J, Cai Y, Zhou J, Wang L, Jiao F, Xu W, Wang Q, Xia S, Lu L, Jiang S. Lan Q, et al. Among authors: zhou j. Microbes Infect. 2021 Sep-Oct;23(8):104840. doi: 10.1016/j.micinf.2021.104840. Epub 2021 May 20. Microbes Infect. 2021. PMID: 34022374 Free PMC article. No abstract available.
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Xia S, Lan Q, Zhu Y, Wang C, Xu W, Li Y, Wang L, Jiao F, Zhou J, Hua C, Wang Q, Cai X, Wu Y, Gao J, Liu H, Sun G, Münch J, Kirchhoff F, Yuan Z, Xie Y, Sun F, Jiang S, Lu L. Xia S, et al. Among authors: zhou j. Signal Transduct Target Ther. 2021 Jul 29;6(1):288. doi: 10.1038/s41392-021-00712-2. Signal Transduct Target Ther. 2021. PMID: 34326308 Free PMC article.
Emerging SARS-CoV-2 variants expand species tropism to murines.
Shuai H, Chan JF, Yuen TT, Yoon C, Hu JC, Wen L, Hu B, Yang D, Wang Y, Hou Y, Huang X, Chai Y, Chan CC, Poon VK, Lu L, Zhang RQ, Chan WM, Ip JD, Chu AW, Hu YF, Cai JP, Chan KH, Zhou J, Sridhar S, Zhang BZ, Yuan S, Zhang AJ, Huang JD, To KK, Yuen KY, Chu H. Shuai H, et al. Among authors: zhou j. EBioMedicine. 2021 Nov;73:103643. doi: 10.1016/j.ebiom.2021.103643. Epub 2021 Oct 21. EBioMedicine. 2021. PMID: 34689086 Free PMC article.
A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs.
Liu Z, Zhou J, Xu W, Deng W, Wang Y, Wang M, Wang Q, Hsieh M, Dong J, Wang X, Huang W, Xing L, He M, Tao C, Xie Y, Zhang Y, Wang Y, Zhao J, Yuan Z, Qin C, Jiang S, Lu L. Liu Z, et al. Among authors: zhou j. Cell Res. 2022 Mar;32(3):269-287. doi: 10.1038/s41422-022-00612-2. Epub 2022 Jan 19. Cell Res. 2022. PMID: 35046518 Free PMC article.
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron.
Shuai H, Chan JF, Hu B, Chai Y, Yuen TT, Yin F, Huang X, Yoon C, Hu JC, Liu H, Shi J, Liu Y, Zhu T, Zhang J, Hou Y, Wang Y, Lu L, Cai JP, Zhang AJ, Zhou J, Yuan S, Brindley MA, Zhang BZ, Huang JD, To KK, Yuen KY, Chu H. Shuai H, et al. Among authors: zhou j. Nature. 2022 Mar;603(7902):693-699. doi: 10.1038/s41586-022-04442-5. Epub 2022 Jan 21. Nature. 2022. PMID: 35062016
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