Prehn JHM - Search Results

1

Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations.

Stachtea X, Loughrey MB, Salvucci M, Lindner AU, Cho S, McDonough E, Sood A, Graf J, Santamaria-Pang A, Corwin A, Laurent-Puig P, Dasgupta S, Shia J, Owens JR, Abate S, Van Schaeybroeck S, Lawler M, Prehn JHM, Ginty F, Longley DB. Stachtea X, et al. Among authors: prehn jhm. Mod Pathol. 2022 Apr;35(4):564-576. doi: 10.1038/s41379-021-00953-0. Epub 2021 Nov 3. Mod Pathol. 2022. PMID: 34732839 Free PMC article.

2

Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review.

Hector S, Prehn JH. Hector S, et al. Biochim Biophys Acta. 2009 Apr;1795(2):117-29. doi: 10.1016/j.bbcan.2008.12.002. Epub 2009 Jan 6. Biochim Biophys Acta. 2009. PMID: 19167459 Free article. Review.

3

Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer.

McCawley N, Conlon S, Hector S, Cummins RJ, Dicker P, Johnston PG, Kay EW, McNamara DA, Prehn JH, Concannon CG. McCawley N, et al. Int J Cancer. 2012 Aug 15;131(4):E494-500. doi: 10.1002/ijc.26468. Epub 2011 Nov 8. Int J Cancer. 2012. PMID: 21960357 Free article.

4

Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer.

Hector S, Conlon S, Schmid J, Dicker P, Cummins RJ, Concannon CG, Johnston PG, Kay EW, Prehn JH. Hector S, et al. Br J Cancer. 2012 Apr 24;106(9):1499-1505. doi: 10.1038/bjc.2012.133. Br J Cancer. 2012. PMID: 22481083 Free PMC article.

5

Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.

Schmid J, Dussmann H, Boukes GJ, Flanagan L, Lindner AU, O'Connor CL, Rehm M, Prehn JH, Huber HJ. Schmid J, et al. J Biol Chem. 2012 Nov 30;287(49):41546-59. doi: 10.1074/jbc.M112.411827. Epub 2012 Oct 4. J Biol Chem. 2012. PMID: 23038270 Free PMC article.

6

Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy.

Lindner AU, Concannon CG, Boukes GJ, Cannon MD, Llambi F, Ryan D, Boland K, Kehoe J, McNamara DA, Murray F, Kay EW, Hector S, Green DR, Huber HJ, Prehn JH. Lindner AU, et al. Cancer Res. 2013 Jan 15;73(2):519-28. doi: 10.1158/0008-5472.CAN-12-2269. Cancer Res. 2013. PMID: 23329644 Free article.

7

The indirect activation model of mitochondrial outer membrane permeabilisation (MOMP) initiation requires a trade-off between robustness in the absence of and sensitivity in the presence of stress.

Lindner AU, Prehn JH, Huber HJ. Lindner AU, et al. Mol Biosyst. 2013 Sep;9(9):2359-69. doi: 10.1039/c3mb70076c. Mol Biosyst. 2013. PMID: 23824068

8

BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer.

Flanagan L, Lindner AU, de Chaumont C, Kehoe J, Fay J, Bacon O, Toomey S, Huber HJ, Hennessy BT, Kay EW, McNamara DA, Prehn JH. Flanagan L, et al. J Mol Med (Berl). 2015 Mar;93(3):315-26. doi: 10.1007/s00109-014-1221-7. Epub 2014 Nov 13. J Mol Med (Berl). 2015. PMID: 25388617

9

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.

Flanagan L, Kehoe J, Fay J, Bacon O, Lindner AU, Kay EW, Deasy J, McNamara DA, Prehn JH. Flanagan L, et al. Radiat Oncol. 2015 Jun 13;10:131. doi: 10.1186/s13014-015-0437-1. Radiat Oncol. 2015. PMID: 26071313 Free PMC article.

10

Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.

Ryan D, Carberry S, Murphy ÁC, Lindner AU, Fay J, Hector S, McCawley N, Bacon O, Concannon CG, Kay EW, McNamara DA, Prehn JH. Ryan D, et al. J Transl Med. 2016 Jul 1;14(1):196. doi: 10.1186/s12967-016-0948-z. J Transl Med. 2016. PMID: 27369741 Free PMC article.

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