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P62 accumulates through neuroanatomical circuits in response to tauopathy propagation.
Blaudin de Thé FX, Lassus B, Schaler AW, Fowler SL, Goulbourne CN, Jeggo R, Mannoury la Cour C, Millan MJ, Duff KE. Blaudin de Thé FX, et al. Among authors: duff ke. Acta Neuropathol Commun. 2021 Nov 2;9(1):177. doi: 10.1186/s40478-021-01280-w. Acta Neuropathol Commun. 2021. PMID: 34727983 Free PMC article.
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.
Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, Dickson D, Duff K. Noble W, et al. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6990-5. doi: 10.1073/pnas.0500466102. Epub 2005 May 2. Proc Natl Acad Sci U S A. 2005. PMID: 15867159 Free PMC article.
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
Fu H, Possenti A, Freer R, Nakano Y, Hernandez Villegas NC, Tang M, Cauhy PVM, Lassus BA, Chen S, Fowler SL, Figueroa HY, Huey ED, Johnson GVW, Vendruscolo M, Duff KE. Fu H, et al. Among authors: duff ke. Nat Neurosci. 2019 Jan;22(1):47-56. doi: 10.1038/s41593-018-0298-7. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559469 Free PMC article.
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, Wemlinger T, Wu M, Kokiko-Cochran ON, Popovich P, Flowers XE, Honig LS, Vonsattel JP, Scharre DW, Beach TG, Ma Q, Kuret J, Kõks S, Urano F, Duff KE, Fu H. Chen S, et al. Among authors: duff ke. Acta Neuropathol. 2022 May;143(5):547-569. doi: 10.1007/s00401-022-02417-4. Epub 2022 Apr 7. Acta Neuropathol. 2022. PMID: 35389045
Trans-synaptic spread of tau pathology in vivo.
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K. Liu L, et al. PLoS One. 2012;7(2):e31302. doi: 10.1371/journal.pone.0031302. Epub 2012 Feb 1. PLoS One. 2012. PMID: 22312444 Free PMC article.
168 results