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Neutralization of vascular endothelial growth factor antiangiogenic isoforms is more effective than treatment with proangiogenic isoforms in stimulating vascular development and follicle progression in the perinatal rat ovary.
Artac RA, McFee RM, Smith RA, Baltes-Breitwisch MM, Clopton DT, Cupp AS. Artac RA, et al. Among authors: mcfee rm. Biol Reprod. 2009 Nov;81(5):978-88. doi: 10.1095/biolreprod.109.078097. Epub 2009 Jul 15. Biol Reprod. 2009. PMID: 19605786 Free PMC article.
Loss of vascular endothelial growth factor A (VEGFA) isoforms in the testes of male mice causes subfertility, reduces sperm numbers, and alters expression of genes that regulate undifferentiated spermatogonia.
Lu N, Sargent KM, Clopton DT, Pohlmeier WE, Brauer VM, McFee RM, Weber JS, Ferrara N, Silversides DW, Cupp AS. Lu N, et al. Among authors: mcfee rm. Endocrinology. 2013 Dec;154(12):4790-802. doi: 10.1210/en.2013-1363. Epub 2013 Oct 29. Endocrinology. 2013. PMID: 24169552 Free PMC article.
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