Al-Sanea MM - Search Results

1

Small Molecules as LIM Kinase Inhibitors.

Bukhari SNA, Tandiary MA, Al-Sanea MM, Abdelgawad MA, Chee CF, Hussain MA. Bukhari SNA, et al. Curr Med Chem. 2022;29(17):2995-3027. doi: 10.2174/0929867328666211026120335. Curr Med Chem. 2022. PMID: 34702151 Review.

2

ROS1 Kinase Inhibitors for Molecular-Targeted Therapies.

Al-Sanea MM, Abdelazem AZ, Park BS, Yoo KH, Sim T, Kwon YJ, Lee SH. Al-Sanea MM, et al. Curr Med Chem. 2016;23(2):142-60. doi: 10.2174/0929867322666151006093623. Curr Med Chem. 2016. PMID: 26438251 Review.

3

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors.

Al-Sanea MM, Elkamhawy A, Paik S, Bua S, Ha Lee S, Abdelgawad MA, Roh EJ, Eldehna WM, Supuran CT. Al-Sanea MM, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1457-1464. doi: 10.1080/14756366.2019.1652282. J Enzyme Inhib Med Chem. 2019. PMID: 31411080 Free PMC article.

4

New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition.

Abdelgawad MA, Bakr RB, Ahmad W, Al-Sanea MM, Elshemy HAH. Abdelgawad MA, et al. Bioorg Chem. 2019 Nov;92:103218. doi: 10.1016/j.bioorg.2019.103218. Epub 2019 Aug 26. Bioorg Chem. 2019. PMID: 31536956

5

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.

Al-Sanea MM, Gotina L, Mohamed MF, Grace Thomas Parambi D, Gomaa HAM, Mathew B, Youssif BGM, Alharbi KS, Elsayed ZM, Abdelgawad MA, Eldehna WM. Al-Sanea MM, et al. Drug Des Devel Ther. 2020 Feb 4;14:497-508. doi: 10.2147/DDDT.S237957. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 32103894 Free PMC article.

6

Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights.

Al-Sanea MM, Elkamhawy A, Paik S, Lee K, El Kerdawy AM, Syed Nasir Abbas B, Joo Roh E, Eldehna WM, Elshemy HAH, Bakr RB, Ali Farahat I, Alzarea AI, Alzarea SI, Alharbi KS, Abdelgawad MA. Al-Sanea MM, et al. Bioorg Med Chem. 2020 Jul 1;28(13):115525. doi: 10.1016/j.bmc.2020.115525. Epub 2020 Apr 25. Bioorg Med Chem. 2020. PMID: 32371117

7

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.

Alkhaldi AAM, Al-Sanea MM, Nocentini A, Eldehna WM, Elsayed ZM, Bonardi A, Abo-Ashour MF, El-Damasy AK, Abdel-Maksoud MS, Al-Warhi T, Gratteri P, Abdel-Aziz HA, Supuran CT, El-Haggar R. Alkhaldi AAM, et al. Eur J Med Chem. 2020 Dec 1;207:112745. doi: 10.1016/j.ejmech.2020.112745. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32877804

8

Evaluation of Ligustrazine-Based Synthetic Compounds for their Antiproliferative Effects.

Bukhari SNA, Alotaibi NH, Ahmad W, Alharbi KS, Abdelgawad MA, Al-Sanea MM, Ahmad MM, Amjad MW, Raja MAG, Hussain MA. Bukhari SNA, et al. Med Chem. 2021;17(9):956-962. doi: 10.2174/1573406416666200905125038. Med Chem. 2021. PMID: 32888274

9

A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights.

Al-Sanea MM, Obaidullah AJ, Shaker ME, Chilingaryan G, Alanazi MM, Alsaif NA, Alkahtani HM, Alsubaie SA, Abdelgawad MA. Al-Sanea MM, et al. Molecules. 2021 Jan 14;26(2):412. doi: 10.3390/molecules26020412. Molecules. 2021. PMID: 33466812 Free PMC article.

10

Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.

Elbadawi MM, Eldehna WM, Nocentini A, Abo-Ashour MF, Elkaeed EB, Abdelgawad MA, Alharbi KS, Abdel-Aziz HA, Supuran CT, Gratteri P, Al-Sanea MM. Elbadawi MM, et al. Eur J Med Chem. 2021 Jun 5;218:113360. doi: 10.1016/j.ejmech.2021.113360. Epub 2021 Mar 13. Eur J Med Chem. 2021. PMID: 33773285

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