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Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3β inhibitors.
La Pietra V, La Regina G, Coluccia A, Famiglini V, Pelliccia S, Plotkin B, Eldar-Finkelman H, Brancale A, Ballatore C, Crowe A, Brunden KR, Marinelli L, Novellino E, Silvestri R. La Pietra V, et al. Among authors: brancale a. J Med Chem. 2013 Dec 27;56(24):10066-78. doi: 10.1021/jm401466v. Epub 2013 Dec 11. J Med Chem. 2013. PMID: 24295046
Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists.
Wang X, Liu L, Huang L, Herbst-Robinson K, Cornec AS, James MJ, Sugiyama S, Bassetto M, Brancale A, Trojanowski JQ, Lee VM, Smith AB 3rd, Brunden KR, Ballatore C. Wang X, et al. Among authors: brancale a. ACS Med Chem Lett. 2014 Jul 24;5(9):1015-20. doi: 10.1021/ml5002085. eCollection 2014 Sep 11. ACS Med Chem Lett. 2014. PMID: 25221659 Free PMC article.
In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation.
Hewitt MG, Morrison PWJ, Boostrom HM, Morgan SR, Fallon M, Lewis PN, Whitaker D, Brancale A, Varricchio C, Quantock AJ, Burton MJ, Heard CM. Hewitt MG, et al. Among authors: brancale a. Mol Pharm. 2020 Apr 6;17(4):1428-1441. doi: 10.1021/acs.molpharmaceut.0c00140. Epub 2020 Mar 20. Mol Pharm. 2020. PMID: 32125863
220 results