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HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD. Cheeseman MT, et al. Among authors: williams d. PLoS Genet. 2011 Oct;7(10):e1002336. doi: 10.1371/journal.pgen.1002336. Epub 2011 Oct 20. PLoS Genet. 2011. PMID: 22028672 Free PMC article.
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.
Goggolidou P, Stevens JL, Agueci F, Keynton J, Wheway G, Grimes DT, Patel SH, Hilton H, Morthorst SK, DiPaolo A, Williams DJ, Sanderson J, Khoronenkova SV, Powles-Glover N, Ermakov A, Esapa CT, Romero R, Dianov GL, Briscoe J, Johnson CA, Pedersen LB, Norris DP. Goggolidou P, et al. Development. 2014 Oct;141(20):3966-77. doi: 10.1242/dev.107755. Development. 2014. PMID: 25294941 Free PMC article.
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.
Bogani D, Siggers P, Brixey R, Warr N, Beddow S, Edwards J, Williams D, Wilhelm D, Koopman P, Flavell RA, Chi H, Ostrer H, Wells S, Cheeseman M, Greenfield A. Bogani D, et al. Among authors: williams d. PLoS Biol. 2009 Sep;7(9):e1000196. doi: 10.1371/journal.pbio.1000196. Epub 2009 Sep 15. PLoS Biol. 2009. PMID: 19753101 Free PMC article.
Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.
Mackenzie FE, Romero R, Williams D, Gillingwater T, Hilton H, Dick J, Riddoch-Contreras J, Wong F, Ireson L, Powles-Glover N, Riley G, Underhill P, Hough T, Arkell R, Greensmith L, Ribchester RR, Blanco G. Mackenzie FE, et al. Among authors: williams d. Hum Mol Genet. 2009 Oct 1;18(19):3553-66. doi: 10.1093/hmg/ddp304. Epub 2009 Jul 4. Hum Mol Genet. 2009. PMID: 19578180 Free PMC article.
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