Georg GI - Search Results

1

TSSK3, a novel target for male contraception, is required for spermiogenesis.

Nayyab S, Gervasi MG, Tourzani DA, Caraballo DA, Jha KN, Teves ME, Cui W, Georg GI, Visconti PE, Salicioni AM. Nayyab S, et al. Among authors: georg gi. Mol Reprod Dev. 2021 Nov;88(11):718-730. doi: 10.1002/mrd.23539. Epub 2021 Oct 8. Mol Reprod Dev. 2021. PMID: 34623009 Free PMC article.

2

Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception†.

Faber EB, Wang N, Georg GI. Faber EB, et al. Among authors: georg gi. Biol Reprod. 2020 Aug 4;103(2):357-367. doi: 10.1093/biolre/ioaa107. Biol Reprod. 2020. PMID: 32543655 Free PMC article. Review.

3

The Na+ and K+ transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception†.

Syeda SS, Sánchez G, McDermott JP, Hong KH, Blanco G, Georg GI. Syeda SS, et al. Among authors: georg gi. Biol Reprod. 2020 Aug 4;103(2):343-356. doi: 10.1093/biolre/ioaa093. Biol Reprod. 2020. PMID: 32588885 Free PMC article. Review.

4

Retinoic acid receptor antagonists for male contraception: current status†.

Noman MAA, Kyzer JL, Chung SSW, Wolgemuth DJ, Georg GI. Noman MAA, et al. Among authors: georg gi. Biol Reprod. 2020 Aug 4;103(2):390-399. doi: 10.1093/biolre/ioaa122. Biol Reprod. 2020. PMID: 32671394 Free PMC article. Review.

5

Recombinant production of enzymatically active male contraceptive drug target hTSSK2 - Localization of the TSKS domain phosphorylated by TSSK2.

Shetty J, Sinville R, Shumilin IA, Minor W, Zhang J, Hawkinson JE, Georg GI, Flickinger CJ, Herr JC. Shetty J, et al. Among authors: georg gi. Protein Expr Purif. 2016 May;121:88-96. doi: 10.1016/j.pep.2016.01.009. Epub 2016 Jan 14. Protein Expr Purif. 2016. PMID: 26777341 Free PMC article.

6

Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2).

Hawkinson JE, Sinville R, Mudaliar D, Shetty J, Ward T, Herr JC, Georg GI. Hawkinson JE, et al. Among authors: georg gi. ChemMedChem. 2017 Nov 22;12(22):1857-1865. doi: 10.1002/cmdc.201700503. Epub 2017 Oct 20. ChemMedChem. 2017. PMID: 28952188 Free PMC article.

7

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception.

Syeda SS, Sánchez G, Hong KH, Hawkinson JE, Georg GI, Blanco G. Syeda SS, et al. Among authors: georg gi. J Med Chem. 2018 Mar 8;61(5):1800-1820. doi: 10.1021/acs.jmedchem.7b00925. Epub 2018 Jan 19. J Med Chem. 2018. PMID: 29291372 Free PMC article.

8

BET proteins: Investigating BRDT as a potential target for male contraception.

Wisniewski A, Georg GI. Wisniewski A, et al. Among authors: georg gi. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126958. doi: 10.1016/j.bmcl.2020.126958. Epub 2020 Jan 21. Bioorg Med Chem Lett. 2020. PMID: 32019712 Free PMC article. Review.

9

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis†.

Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT. Hanna CB, et al. Among authors: georg gi. Biol Reprod. 2020 Aug 4;103(2):368-377. doi: 10.1093/biolre/ioaa097. Biol Reprod. 2020. PMID: 32667031 Free PMC article.

10

N-Butyldeoxygalactonojirimycin Induces Reversible Infertility in Male CD Rats.

Gupta V, Hild SA, Jakkaraj SR, Carlson EJ, Wong HL, Allen CL, Georg GI, Tash JS. Gupta V, et al. Among authors: georg gi. Int J Mol Sci. 2019 Dec 31;21(1):301. doi: 10.3390/ijms21010301. Int J Mol Sci. 2019. PMID: 31906257 Free PMC article.

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