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Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing ER stress.
J Exp Med. 2021 Dec 6;218(12):e20211035. doi: 10.1084/jem.20211035. Epub 2021 Sep 29.
J Exp Med. 2021.
PMID: 34586341
Free PMC article.
αv Integrins regulate germinal center B cell responses through noncanonical autophagy.
Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, Stuart LM, Orr MT, Rawlings DJ, Jackson SW, Lacy-Hulbert A, Acharya M.
Raso F, et al. Among authors: sagadiev s.
J Clin Invest. 2018 Aug 31;128(9):4163-4178. doi: 10.1172/JCI99597. Epub 2018 Aug 20.
J Clin Invest. 2018.
PMID: 29999501
Free PMC article.
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Transcriptomic analysis of pathways associated with ITGAV/alpha(v) integrin-dependent autophagy in human B cells.
Muir V, Sagadiev S, Liu S, Holder U, Armendariz AM, Suchland E, Meitlis I, Camp N, Giltiay N, Tam JM, Garner EC, Wivagg CN, Shows D, James RG, Lacy-Hulbert A, Acharya M.
Muir V, et al. Among authors: sagadiev s.
Autophagy. 2023 Mar;19(3):926-942. doi: 10.1080/15548627.2022.2113296. Epub 2022 Aug 25.
Autophagy. 2023.
PMID: 36016494
Free PMC article.
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B Cell αv Integrins Regulate TLR-Driven Autoimmunity.
Acharya M, Raso F, Sagadiev S, Gilbertson E, Kadavy L, Li QZ, Yan M, Stuart LM, Hamerman JA, Lacy-Hulbert A.
Acharya M, et al. Among authors: sagadiev s.
J Immunol. 2020 Oct 1;205(7):1810-1818. doi: 10.4049/jimmunol.1901056. Epub 2020 Aug 28.
J Immunol. 2020.
PMID: 32859730
Free PMC article.
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C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.
Wu Y, Mahtal N, Paillares E, Swistak L, Sagadiev S, Acharya M, Demeret C, Werf SV, Guivel-Benhassine F, Schwartz O, Petracchini S, Mettouchi A, Caramelle L, Couvineau P, Thai R, Barbe P, Keck M, Brodin P, Machelart A, Sencio V, Trottein F, Sachse M, Chicanne G, Payrastre B, Ville F, Kreis V, Popoff MR, Johannes L, Cintrat JC, Barbier J, Gillet D, Lemichez E.
Wu Y, et al. Among authors: sagadiev s.
iScience. 2022 Jun 6;25(7):104537. doi: 10.1016/j.isci.2022.104537. eCollection 2022 Jul 15.
iScience. 2022.
PMID: 35769882
Free PMC article.
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Autophagy Induced by Toll-like Receptor Ligands Regulates Antigen Extraction and Presentation by B Cells.
Lagos J, Sagadiev S, Diaz J, Bozo JP, Guzman F, Stefani C, Zanlungo S, Acharya M, Yuseff MI.
Lagos J, et al. Among authors: sagadiev s.
Cells. 2022 Dec 1;11(23):3883. doi: 10.3390/cells11233883.
Cells. 2022.
PMID: 36497137
Free PMC article.
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