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Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.
Lee KJ, Chang WL, Chen X, Valiyaveettil J, Ramirez-Alcantara V, Gavin E, Musiyenko A, Madeira da Silva L, Annamdevula NS, Leavesley SJ, Ward A, Mattox T, Lindsey AS, Andrews J, Zhu B, Wood C, Neese A, Nguyen A, Berry K, Maxuitenko Y, Moyer MP, Nurmemmedov E, Gorman G, Coward L, Zhou G, Keeton AB, Cooper HS, Clapper ML, Piazza GA. Lee KJ, et al. Among authors: ward a. Cancer Prev Res (Phila). 2021 Nov;14(11):995-1008. doi: 10.1158/1940-6207.CAPR-21-0208. Epub 2021 Sep 28. Cancer Prev Res (Phila). 2021. PMID: 34584001 Free PMC article.
Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.
Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Among authors: ward a. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer.
Borneman RM, Gavin E, Musiyenko A, Richter W, Lee KJ, Crossman DK, Andrews JF, Wilhite AM, McClellan S, Aragon I, Ward AB, Chen X, Keeton AB, Berry K, Piazza GA, Scalici JM, da Silva LM. Borneman RM, et al. Among authors: ward ab. J Ovarian Res. 2022 Nov 2;15(1):120. doi: 10.1186/s13048-022-01050-9. J Ovarian Res. 2022. PMID: 36324187 Free PMC article.
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Ganji PN, Maxuitenko Y, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V, Abdelkarim H, Mitra AK, Boyd MR, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. Among authors: ward ab. bioRxiv [Preprint]. 2024 Jan 24:2023.05.17.541233. doi: 10.1101/2023.05.17.541233. bioRxiv. 2024. PMID: 38328254 Free PMC article. Preprint.
The histone methyltransferase SETD2 regulates HIV expression and latency.
Bussey-Sutton CR, Ward A, Fox JA, Turner AW, Peterson JJ, Emery A, Longoria AR, Gomez-Martinez I, Jones C, Hepperla A, Margolis DM, Strahl BD, Browne EP. Bussey-Sutton CR, et al. Among authors: ward a. PLoS Pathog. 2024 Jun 7;20(6):e1012281. doi: 10.1371/journal.ppat.1012281. Online ahead of print. PLoS Pathog. 2024. PMID: 38848441
Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes.
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Burbach S, Truong A, Stubbington MJT, Burton DR, Andrabi R, Ward AB, McDonnell WJ, Briney B. Hurtado J, et al. Among authors: ward ab. Cell Rep. 2024 Jun 5;43(6):114307. doi: 10.1016/j.celrep.2024.114307. Online ahead of print. Cell Rep. 2024. PMID: 38848216
Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
Wolters RM, Ferguson JA, Nuñez IA, Chen EE, Sornberger T, Myers L, Oeverdieck S, Raghavan SSR, Kona C, Handal LS, Esilu TE, Davidson E, Doranz BJ, Engdahl TB, Kose N, Williamson LE, Creech CB, Gibson-Corley KN, Ward AB, Crowe JE Jr. Wolters RM, et al. Among authors: ward ab. Immunity. 2024 May 29:S1074-7613(24)00253-X. doi: 10.1016/j.immuni.2024.05.002. Online ahead of print. Immunity. 2024. PMID: 38823390
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research.
Olmo F, Jayawardhana S, Khan AA, Langston HC, Francisco AF, Atherton RL, Ward AI, Taylor MC, Kelly JM, Lewis MD. Olmo F, et al. Among authors: ward ai. PLoS Negl Trop Dis. 2024 May 31;18(5):e0012106. doi: 10.1371/journal.pntd.0012106. Online ahead of print. PLoS Negl Trop Dis. 2024. PMID: 38820564 Free article.
3,251 results