Sinclair LV - Search Results

1

A glutamine 'tug-of-war': targets to manipulate glutamine metabolism for cancer immunotherapy.

Pallett LJ, Dimeloe S, Sinclair LV, Byrne AJ, Schurich A. Pallett LJ, et al. Among authors: sinclair lv. Immunother Adv. 2021 Jun 1;1(1):ltab010. doi: 10.1093/immadv/ltab010. eCollection 2021 Jan. Immunother Adv. 2021. PMID: 34541580 Free PMC article. Review.

2

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

Pallett LJ, Gill US, Quaglia A, Sinclair LV, Jover-Cobos M, Schurich A, Singh KP, Thomas N, Das A, Chen A, Fusai G, Bertoletti A, Cantrell DA, Kennedy PT, Davies NA, Haniffa M, Maini MK. Pallett LJ, et al. Among authors: sinclair lv. Nat Med. 2015 Jun;21(6):591-600. doi: 10.1038/nm.3856. Epub 2015 May 11. Nat Med. 2015. PMID: 25962123 Free PMC article.

3

Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.

Jenkins BJ, Blagih J, Ponce-Garcia FM, Canavan M, Gudgeon N, Eastham S, Hill D, Hanlon MM, Ma EH, Bishop EL, Rees A, Cronin JG, Jury EC, Dimeloe SK, Veale DJ, Thornton CA, Vousden KH, Finlay DK, Fearon U, Jones GW, Sinclair LV, Vincent EE, Jones N. Jenkins BJ, et al. Among authors: sinclair lv. Cell Metab. 2023 Jul 11;35(7):1132-1146.e9. doi: 10.1016/j.cmet.2023.05.001. Epub 2023 May 24. Cell Metab. 2023. PMID: 37230079 Free article.

4

Extracellular vesicles in COVID-19 convalescence can regulate T cell metabolism and function.

George MS, Sanchez J, Rollings C, Fear D, Irving P, Sinclair LV, Schurich A. George MS, et al. Among authors: sinclair lv. iScience. 2023 Jul 4;26(8):107280. doi: 10.1016/j.isci.2023.107280. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520724 Free PMC article.

5

Nutrient sensing, signal transduction and immune responses.

Walls J, Sinclair L, Finlay D. Walls J, et al. Semin Immunol. 2016 Oct;28(5):396-407. doi: 10.1016/j.smim.2016.09.001. Epub 2016 Sep 24. Semin Immunol. 2016. PMID: 27681670 Review.

6

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation.

Sinclair LV, Rolf J, Emslie E, Shi YB, Taylor PM, Cantrell DA. Sinclair LV, et al. Nat Immunol. 2013 May;14(5):500-8. doi: 10.1038/ni.2556. Epub 2013 Mar 24. Nat Immunol. 2013. PMID: 23525088 Free PMC article.

7

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.

Swamy M, Pathak S, Grzes KM, Damerow S, Sinclair LV, van Aalten DM, Cantrell DA. Swamy M, et al. Among authors: sinclair lv. Nat Immunol. 2016 Jun;17(6):712-20. doi: 10.1038/ni.3439. Epub 2016 Apr 25. Nat Immunol. 2016. PMID: 27111141 Free PMC article.

8

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation.

Marchingo JM, Sinclair LV, Howden AJ, Cantrell DA. Marchingo JM, et al. Among authors: sinclair lv. Elife. 2020 Feb 5;9:e53725. doi: 10.7554/eLife.53725. Elife. 2020. PMID: 32022686 Free PMC article.

9

Differential regulation of T-cell growth by IL-2 and IL-15.

Cornish GH, Sinclair LV, Cantrell DA. Cornish GH, et al. Among authors: sinclair lv. Blood. 2006 Jul 15;108(2):600-8. doi: 10.1182/blood-2005-12-4827. Epub 2006 Mar 28. Blood. 2006. PMID: 16569767 Free article.

10

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.

Sinclair LV, Finlay D, Feijoo C, Cornish GH, Gray A, Ager A, Okkenhaug K, Hagenbeek TJ, Spits H, Cantrell DA. Sinclair LV, et al. Nat Immunol. 2008 May;9(5):513-21. doi: 10.1038/ni.1603. Epub 2008 Apr 6. Nat Immunol. 2008. PMID: 18391955 Free PMC article.

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