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Page 1
Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis.
Wang VE, Blaser BW, Patel RK, Behbehani GK, Rao AA, Durbin-Johnson B, Jiang T, Logan AC, Settles M, Mannis GN, Olin R, Damon LE, Martin TG, Sayre PH, Gaensler KM, McMahon E, Flanders M, Weinberg V, Ye CJ, Carbone DP, Munster PN, Fragiadakis GK, McCormick F, Andreadis C. Wang VE, et al. Among authors: patel rk. Blood Cancer Discov. 2021 Sep;2(5):434-449. doi: 10.1158/2643-3230.BCD-21-0055. Epub 2021 Jul 16. Blood Cancer Discov. 2021. PMID: 34514432 Free PMC article.
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia.
Eisfeld AK, Marcucci G, Maharry K, Schwind S, Radmacher MD, Nicolet D, Becker H, Mrózek K, Whitman SP, Metzeler KH, Mendler JH, Wu YZ, Liyanarachchi S, Patel R, Baer MR, Powell BL, Carter TH, Moore JO, Kolitz JE, Wetzler M, Caligiuri MA, Larson RA, Tanner SM, de la Chapelle A, Bloomfield CD. Eisfeld AK, et al. Blood. 2012 Jul 12;120(2):249-58. doi: 10.1182/blood-2012-02-408492. Epub 2012 Apr 23. Blood. 2012. PMID: 22529287 Free PMC article.
Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis.
Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. Mennillo E, et al. Among authors: patel rk. Nat Commun. 2024 Feb 19;15(1):1493. doi: 10.1038/s41467-024-45665-6. Nat Commun. 2024. PMID: 38374043 Free PMC article.
Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway.
Eisfeld AK, Schwind S, Patel R, Huang X, Santhanam R, Walker CJ, Markowitz J, Hoag KW, Jarvinen TM, Leffel B, Perrotti D, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A. Eisfeld AK, et al. Sci Signal. 2014 Apr 15;7(321):ra36. doi: 10.1126/scisignal.2004762. Sci Signal. 2014. PMID: 24736457 Free PMC article.
NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.
Eisfeld AK, Schwind S, Hoag KW, Walker CJ, Liyanarachchi S, Patel R, Huang X, Markowitz J, Duan W, Otterson GA, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A. Eisfeld AK, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4179-84. doi: 10.1073/pnas.1401727111. Epub 2014 Feb 28. Proc Natl Acad Sci U S A. 2014. PMID: 24586049 Free PMC article.
Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Network I, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf J, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Augustine AD, Sekaly RP, Ehrlich LIR, Fourati S, Peters B, Kleinstein SH, Guan L. Gygi JP, et al. Among authors: patel rk. bioRxiv [Preprint]. 2023 Nov 6:2023.11.03.565292. doi: 10.1101/2023.11.03.565292. bioRxiv. 2023. PMID: 37986828 Free PMC article. Updated. Preprint.
MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies.
Lankenau MA, Patel R, Liyanarachchi S, Maharry SE, Hoag KW, Duggan M, Walker CJ, Markowitz J, Carson WE 3rd, Eisfeld AK, de la Chapelle A. Lankenau MA, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):E6744-51. doi: 10.1073/pnas.1520390112. Epub 2015 Nov 18. Proc Natl Acad Sci U S A. 2015. PMID: 26582795 Free PMC article.
Native myocardial T1 and right ventricular size by CMR predict outcome in systemic sclerosis-associated pulmonary hypertension.
Knight DS, Virsinskaite R, Karia N, Cole AR, Maclean RH, Brown JT, Patel RK, Razvi Y, Venneri L, Kotecha T, Martinez-Naharro A, Kellman P, Scott-Russell AM, Schreiber BE, Ong VH, Denton CP, Fontana M, Coghlan JG, Muthurangu V. Knight DS, et al. Among authors: patel rk. Rheumatology (Oxford). 2024 May 17:keae141. doi: 10.1093/rheumatology/keae141. Online ahead of print. Rheumatology (Oxford). 2024. PMID: 38759116
444 results