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Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605).
Pietrofesa RA, Park K, Mishra OP, Johnson-McDaniel D, Myerson JW, Shuvaev VV, Arguiri E, Chatterjee S, Moorthy GS, Zuppa A, Hwang WT, Christofidou-Solomidou M. Pietrofesa RA, et al. Among authors: myerson jw. Int J Mol Sci. 2021 Aug 31;22(17):9477. doi: 10.3390/ijms22179477. Int J Mol Sci. 2021. PMID: 34502389 Free PMC article.
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions.
Brenner JS, Bhamidipati K, Glassman PM, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa CH, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Brenner JS, et al. Among authors: myerson jw. Nanomedicine. 2017 May;13(4):1495-1506. doi: 10.1016/j.nano.2016.12.019. Epub 2017 Jan 5. Nanomedicine. 2017. PMID: 28065731 Free PMC article.
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude.
Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, Shuvaeva T, Khoshnejad M, Johnston I, Gregory JV, Lahann J, Wang T, Cantu E, Armstead WM, Mitragotri S, Muzykantov V. Brenner JS, et al. Among authors: myerson jw. Nat Commun. 2018 Jul 11;9(1):2684. doi: 10.1038/s41467-018-05079-7. Nat Commun. 2018. PMID: 29992966 Free PMC article.
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.
Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, Shuvaev VV, Nong J, Brenner JS, Khoshnejad M, Madden T, Weissmann D, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. Among authors: myerson jw. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3405-3414. doi: 10.1073/pnas.1912012117. Epub 2020 Jan 31. Proc Natl Acad Sci U S A. 2020. PMID: 32005712 Free PMC article.
Targeting drug delivery in the vascular system: Focus on endothelium.
Glassman PM, Myerson JW, Ferguson LT, Kiseleva RY, Shuvaev VV, Brenner JS, Muzykantov VR. Glassman PM, et al. Among authors: myerson jw. Adv Drug Deliv Rev. 2020;157:96-117. doi: 10.1016/j.addr.2020.06.013. Epub 2020 Jun 21. Adv Drug Deliv Rev. 2020. PMID: 32579890 Free PMC article. Review.
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
Parhiz H, Brenner JS, Patel PN, Papp TE, Shahnawaz H, Li Q, Shi R, Zamora ME, Yadegari A, Marcos-Contreras OA, Natesan A, Pardi N, Shuvaev VV, Kiseleva R, Myerson JW, Uhler T, Riley RS, Han X, Mitchell MJ, Lam K, Heyes J, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: myerson jw. J Control Release. 2022 Apr;344:50-61. doi: 10.1016/j.jconrel.2021.12.027. Epub 2021 Dec 23. J Control Release. 2022. PMID: 34953981 Free PMC article.
48 results