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Characterization of Compound-Specific, Concentration-Independent Biophysical Properties of Sodium Channel Inhibitor Mechanism of Action Using Automated Patch-Clamp Electrophysiology.
Front Pharmacol. 2021 Aug 23;12:738460. doi: 10.3389/fphar.2021.738460. eCollection 2021.
Front Pharmacol. 2021.
PMID: 34497526
Free PMC article.
The mechanism of non-blocking inhibition of sodium channels revealed by conformation-selective photolabeling.
Földi MC, Pesti K, Zboray K, Toth AV, Hegedűs T, Málnási-Csizmadia A, Lukacs P, Mike A.
Földi MC, et al.
Br J Pharmacol. 2021 Mar;178(5):1200-1217. doi: 10.1111/bph.15365. Epub 2021 Feb 1.
Br J Pharmacol. 2021.
PMID: 33450052
Free article.
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An Advanced Automated Patch Clamp Protocol Design to Investigate Drug-Ion Channel Binding Dynamics.
Lukacs P, Pesti K, Földi MC, Zboray K, Toth AV, Papp G, Mike A.
Lukacs P, et al. Among authors: foldi mc.
Front Pharmacol. 2021 Sep 28;12:738260. doi: 10.3389/fphar.2021.738260. eCollection 2021.
Front Pharmacol. 2021.
PMID: 34658875
Free PMC article.
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The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels.
Hackl B, Lukacs P, Ebner J, Pesti K, Haechl N, Földi MC, Lilliu E, Schicker K, Kubista H, Stary-Weinzinger A, Hilber K, Mike A, Todt H, Koenig X.
Hackl B, et al. Among authors: foldi mc.
Front Pharmacol. 2022 May 2;13:809802. doi: 10.3389/fphar.2022.809802. eCollection 2022.
Front Pharmacol. 2022.
PMID: 35586063
Free PMC article.
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Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog.
Lukacs P, Földi MC, Valánszki L, Casanova E, Biri-Kovács B, Nyitray L, Málnási-Csizmadia A, Mike A.
Lukacs P, et al. Among authors: foldi mc.
Sci Rep. 2018 May 25;8(1):8110. doi: 10.1038/s41598-018-26444-y.
Sci Rep. 2018.
PMID: 29802266
Free PMC article.
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