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Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse.
Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T, Granberg KJ, Lamb AD, Ketola K, Mills IG, Attard G, Wang W, Nykter M, Urbanucci A. Taavitsainen S, et al. Among authors: nykter m. Nat Commun. 2021 Sep 6;12(1):5307. doi: 10.1038/s41467-021-25624-1. Nat Commun. 2021. PMID: 34489465 Free PMC article.
The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma.
Parker BC, Annala MJ, Cogdell DE, Granberg KJ, Sun Y, Ji P, Li X, Gumin J, Zheng H, Hu L, Yli-Harja O, Haapasalo H, Visakorpi T, Liu X, Liu CG, Sawaya R, Fuller GN, Chen K, Lang FF, Nykter M, Zhang W. Parker BC, et al. Among authors: nykter m. J Clin Invest. 2013 Feb;123(2):855-65. doi: 10.1172/JCI67144. Epub 2013 Jan 9. J Clin Invest. 2013. PMID: 23298836 Free PMC article.
Overexpression of SNORD114-3 marks acute promyelocytic leukemia.
Liuksiala T, Teittinen KJ, Granberg K, Heinäniemi M, Annala M, Mäki M, Nykter M, Lohi O. Liuksiala T, et al. Among authors: nykter m. Leukemia. 2014 Jan;28(1):233-6. doi: 10.1038/leu.2013.250. Epub 2013 Aug 27. Leukemia. 2014. PMID: 23979522 No abstract available.
Loss of PTEN is associated with aggressive behavior in ERG-positive prostate cancer.
Leinonen KA, Saramäki OR, Furusato B, Kimura T, Takahashi H, Egawa S, Suzuki H, Keiger K, Ho Hahm S, Isaacs WB, Tolonen TT, Stenman UH, Tammela TL, Nykter M, Bova GS, Visakorpi T. Leinonen KA, et al. Among authors: nykter m. Cancer Epidemiol Biomarkers Prev. 2013 Dec;22(12):2333-44. doi: 10.1158/1055-9965.EPI-13-0333-T. Epub 2013 Oct 1. Cancer Epidemiol Biomarkers Prev. 2013. PMID: 24083995 Free PMC article.
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding.
Huang Q, Whitington T, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J, Wei GH. Huang Q, et al. Among authors: nykter m. Nat Genet. 2014 Feb;46(2):126-35. doi: 10.1038/ng.2862. Epub 2014 Jan 5. Nat Genet. 2014. PMID: 24390282
DOT1L-HES6 fusion drives androgen independent growth in prostate cancer.
Annala M, Kivinummi K, Leinonen K, Tuominen J, Zhang W, Visakorpi T, Nykter M. Annala M, et al. Among authors: nykter m. EMBO Mol Med. 2014 Sep;6(9):1121-3. doi: 10.15252/emmm.201404210. EMBO Mol Med. 2014. PMID: 25006183 Free PMC article. No abstract available.
Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.
Turner KM, Sun Y, Ji P, Granberg KJ, Bernard B, Hu L, Cogdell DE, Zhou X, Yli-Harja O, Nykter M, Shmulevich I, Yung WK, Fuller GN, Zhang W. Turner KM, et al. Among authors: nykter m. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3421-6. doi: 10.1073/pnas.1414573112. Epub 2015 Mar 3. Proc Natl Acad Sci U S A. 2015. PMID: 25737557 Free PMC article.
167 results