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Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse.
Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T, Granberg KJ, Lamb AD, Ketola K, Mills IG, Attard G, Wang W, Nykter M, Urbanucci A. Taavitsainen S, et al. Among authors: kaarijarvi r. Nat Commun. 2021 Sep 6;12(1):5307. doi: 10.1038/s41467-021-25624-1. Nat Commun. 2021. PMID: 34489465 Free PMC article.
Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity.
Ketola K, Kaljunen H, Taavitsainen S, Kaarijärvi R, Järvelä E, Rodríguez-Martín B, Haase K, Woodcock DJ, Tubio J, Wedge DC, Nykter M, Bova GS. Ketola K, et al. Among authors: kaarijarvi r. Cancer Res. 2021 Oct 1;81(19):4901-4909. doi: 10.1158/0008-5472.CAN-21-0371. Epub 2021 Sep 8. Cancer Res. 2021. PMID: 34348967 Free PMC article.
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2.
Kaarijärvi R, Kaljunen H, Nappi L, Fazli L, Kung SHY, Hartikainen JM, Paakinaho V, Capra J, Rilla K, Malinen M, Mäkinen PI, Ylä-Herttuala S, Zoubeidi A, Wang Y, Gleave ME, Hiltunen M, Ketola K. Kaarijärvi R, et al. Commun Biol. 2024 Jan 18;7(1):108. doi: 10.1038/s42003-023-05741-x. Commun Biol. 2024. PMID: 38238517 Free PMC article.
Fanconi anemia pathway regulation by FANCI in prostate cancer.
Kaljunen H, Taavitsainen S, Kaarijärvi R, Takala E, Paakinaho V, Nykter M, Bova GS, Ketola K. Kaljunen H, et al. Among authors: kaarijarvi r. Front Oncol. 2023 Oct 30;13:1260826. doi: 10.3389/fonc.2023.1260826. eCollection 2023. Front Oncol. 2023. PMID: 38023254 Free PMC article.