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Exploration of Pyrazolo[1,5-a]pyrimidines as Membrane-Bound Pyrophosphatase Inhibitors.
Johansson NG, Dreano L, Vidilaseris K, Khattab A, Liu J, Lasbleiz A, Ribeiro O, Kiriazis A, Boije Af Gennäs G, Meri S, Goldman A, Yli-Kauhaluoma J, Xhaard H. Johansson NG, et al. Among authors: xhaard h. ChemMedChem. 2021 Nov 5;16(21):3360-3367. doi: 10.1002/cmdc.202100392. Epub 2021 Oct 12. ChemMedChem. 2021. PMID: 34459148 Free PMC article.
[Pyrophosphate in medicine].
Goldman A, Boije af Gennis G, Xhaard H, Meri S, Yli-Kauhaluoma J. Goldman A, et al. Among authors: xhaard h. Duodecim. 2016;132(12):1111-7. Duodecim. 2016. PMID: 27483627 Review. Finnish.
Structural Isosteres of Phosphate Groups in the Protein Data Bank.
Zhang Y, Borrel A, Ghemtio L, Regad L, Boije Af Gennäs G, Camproux AC, Yli-Kauhaluoma J, Xhaard H. Zhang Y, et al. Among authors: xhaard h. J Chem Inf Model. 2017 Mar 27;57(3):499-516. doi: 10.1021/acs.jcim.6b00519. Epub 2017 Mar 13. J Chem Inf Model. 2017. PMID: 28234462
Adenosine analogs bearing phosphate isosteres as human MDO1 ligands.
Zhang Y, Jumppanen M, Maksimainen MM, Auno S, Awol Z, Ghemtio L, Venkannagari H, Lehtiö L, Yli-Kauhaluoma J, Xhaard H, Boije Af Gennäs G. Zhang Y, et al. Among authors: xhaard h. Bioorg Med Chem. 2018 May 1;26(8):1588-1597. doi: 10.1016/j.bmc.2018.02.006. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29501416
Azulene-based compounds for targeting orexin receptors.
Leino TO, Turku A, Yli-Kauhaluoma J, Kukkonen JP, Xhaard H, Wallén EAA. Leino TO, et al. Among authors: xhaard h. Eur J Med Chem. 2018 Sep 5;157:88-100. doi: 10.1016/j.ejmech.2018.07.040. Epub 2018 Jul 20. Eur J Med Chem. 2018. PMID: 30077889
58 results