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Mechanism-based inhibitors of SIRT2: structure-activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration.
Nielsen AL, Rajabi N, Kudo N, Lundø K, Moreno-Yruela C, Bæk M, Fontenas M, Lucidi A, Madsen AS, Yoshida M, Olsen CA. Nielsen AL, et al. Among authors: fontenas m. RSC Chem Biol. 2021 Jan 14;2(2):612-626. doi: 10.1039/d0cb00036a. eCollection 2021 Apr 1. RSC Chem Biol. 2021. PMID: 34458803 Free PMC article.
Ribosomal RNA 2'-O-methylation dynamics impact cell fate decisions.
Häfner SJ, Jansson MD, Altinel K, Andersen KL, Abay-Nørgaard Z, Ménard P, Fontenas M, Sørensen DM, Gay DM, Arendrup FS, Tehler D, Krogh N, Nielsen H, Kraushar ML, Kirkeby A, Lund AH. Häfner SJ, et al. Among authors: fontenas m. Dev Cell. 2023 Sep 11;58(17):1593-1609.e9. doi: 10.1016/j.devcel.2023.06.007. Epub 2023 Jul 19. Dev Cell. 2023. PMID: 37473757