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Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Jíchová Š, Kopkan L, Husková Z, Doleželová Š, Neckář J, Kujal P, Vernerová Z, Kramer HJ, Sadowski J, Kompanowska-Jezierska E, Reddy RN, Falck JR, Imig JD, Červenka L. Jíchová Š, et al. J Hypertens. 2016 Oct;34(10):2008-25. doi: 10.1097/HJH.0000000000001029. J Hypertens. 2016. PMID: 27428043 Free PMC article.
Fenofibrate Attenuates Hypertension in Goldblatt Hypertensive Rats: Role of 20-Hydroxyeicosatetraenoic Acid in the Nonclipped Kidney.
Sporková A, Čertíková Chábová V, Doleželová Š, Jíchová Š, Kopkan L, Vaňourková Z, Kompanowska-Jezierska E, Sadowski J, Maxová H, Červenka L. Sporková A, et al. Among authors: jichova s. Am J Med Sci. 2017 Jun;353(6):568-579. doi: 10.1016/j.amjms.2017.04.009. Epub 2017 Apr 12. Am J Med Sci. 2017. PMID: 28641720
Deleterious Effects of Hyperactivity of the Renin-Angiotensin System and Hypertension on the Course of Chemotherapy-Induced Heart Failure after Doxorubicin Administration: A Study in Ren-2 Transgenic Rat.
Kala P, Bartušková H, Piťha J, Vaňourková Z, Kikerlová S, Jíchová Š, Melenovský V, Hošková L, Veselka J, Kompanowska-Jezierska E, Sadowski J, Gawrys O, Maxová H, Červenka L. Kala P, et al. Among authors: jichova s. Int J Mol Sci. 2020 Dec 8;21(24):9337. doi: 10.3390/ijms21249337. Int J Mol Sci. 2020. PMID: 33302374 Free PMC article.
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Honetschlagerová Z, Gawrys O, Jíchová Š, Škaroupková P, Kikerlová S, Vaňourková Z, Husková Z, Melenovský V, Kompanowska-Jezierska E, Sadowski J, Kolář F, Novotný J, Hejnová L, Kujal P, Červenka L. Honetschlagerová Z, et al. Among authors: jichova s. Kidney Blood Press Res. 2021;46(1):95-113. doi: 10.1159/000513071. Epub 2021 Feb 2. Kidney Blood Press Res. 2021. PMID: 33530085 Free article.
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Sporková A, et al. Among authors: jichova s. Clin Exp Pharmacol Physiol. 2014 Dec;41(12):1003-13. doi: 10.1111/1440-1681.12310. Clin Exp Pharmacol Physiol. 2014. PMID: 25224811 Free PMC article.
Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.
Alánová P, Husková Z, Kopkan L, Sporková A, Jíchová Š, Neckář J, Imig JD, Klevstig M, Kolář F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovský V, Červenková L, Kujal P, Vernerová Z, Červenka L. Alánová P, et al. Among authors: jichova s. Vascul Pharmacol. 2015 Oct;73:45-56. doi: 10.1016/j.vph.2015.08.013. Epub 2015 Aug 22. Vascul Pharmacol. 2015. PMID: 26304700
Progression of hypertension and kidney disease in aging fawn-hooded rats is mediated by enhanced influence of renin-angiotensin system and suppression of nitric oxide system and epoxyeicosanoids.
Doleželová Š, Jíchová Š, Husková Z, Vojtíšková A, Kujal P, Hošková L, Kautzner J, Sadowski J, Červenka L, Kopkan L. Doleželová Š, et al. Among authors: jichova s. Clin Exp Hypertens. 2016;38(7):644-651. doi: 10.1080/10641963.2016.1182182. Epub 2016 Sep 26. Clin Exp Hypertens. 2016. PMID: 27669111
Effects of Epoxyeicosatrienoic Acid-Enhancing Therapy on the Course of Congestive Heart Failure in Angiotensin II-Dependent Rat Hypertension: From mRNA Analysis towards Functional In Vivo Evaluation.
Kala P, Miklovič M, Jíchová Š, Škaroupková P, Vaňourková Z, Maxová H, Gawrys O, Kompanowska-Jezierska E, Sadowski J, Imig JD, Falck JR, Veselka J, Červenka L, Aiglová R, Vícha M, Gloger V, Táborský M. Kala P, et al. Among authors: jichova s. Biomedicines. 2021 Aug 20;9(8):1053. doi: 10.3390/biomedicines9081053. Biomedicines. 2021. PMID: 34440257 Free PMC article.
15 results