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Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice.
Cansell C, Stobbe K, Sanchez C, Le Thuc O, Mosser CA, Ben-Fradj S, Leredde J, Lebeaupin C, Debayle D, Fleuriot L, Brau F, Devaux N, Benani A, Audinat E, Blondeau N, Nahon JL, Rovère C. Cansell C, et al. Among authors: le thuc o. Glia. 2021 Jan;69(1):42-60. doi: 10.1002/glia.23882. Epub 2020 Jul 13. Glia. 2021. PMID: 32659044
Effects of sleeve gastrectomy in high fat diet-induced obese mice: respective role of reduced caloric intake, white adipose tissue inflammation and changes in adipose tissue and ectopic fat depots.
Schneck AS, Iannelli A, Patouraux S, Rousseau D, Bonnafous S, Bailly-Maitre B, Le Thuc O, Rovere C, Panaia-Ferrari P, Anty R, Tran A, Gual P, Gugenheim J. Schneck AS, et al. Among authors: le thuc o. Surg Endosc. 2014 Feb;28(2):592-602. doi: 10.1007/s00464-013-3211-1. Epub 2013 Oct 3. Surg Endosc. 2014. PMID: 24196540
ER stress induces NLRP3 inflammasome activation and hepatocyte death.
Lebeaupin C, Proics E, de Bieville CH, Rousseau D, Bonnafous S, Patouraux S, Adam G, Lavallard VJ, Rovere C, Le Thuc O, Saint-Paul MC, Anty R, Schneck AS, Iannelli A, Gugenheim J, Tran A, Gual P, Bailly-Maitre B. Lebeaupin C, et al. Among authors: le thuc o. Cell Death Dis. 2015 Sep 10;6(9):e1879. doi: 10.1038/cddis.2015.248. Cell Death Dis. 2015. PMID: 26355342 Free PMC article.
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.
Gruber T, Pan C, Contreras RE, Wiedemann T, Morgan DA, Skowronski AA, Lefort S, De Bernardis Murat C, Le Thuc O, Legutko B, Ruiz-Ojeda FJ, Fuente-Fernández M, García-Villalón AL, González-Hedström D, Huber M, Szigeti-Buck K, Müller TD, Ussar S, Pfluger P, Woods SC, Ertürk A, LeDuc CA, Rahmouni K, Granado M, Horvath TL, Tschöp MH, García-Cáceres C. Gruber T, et al. Among authors: le thuc o. Cell Metab. 2021 Jun 1;33(6):1155-1170.e10. doi: 10.1016/j.cmet.2021.04.007. Epub 2021 May 4. Cell Metab. 2021. PMID: 33951475 Free PMC article.
18 results