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T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8.
Tran MT, Faridi P, Lim JJ, Ting YT, Onwukwe G, Bhattacharjee P, Jones CM, Tresoldi E, Cameron FJ, La Gruta NL, Purcell AW, Mannering SI, Rossjohn J, Reid HH. Tran MT, et al. Among authors: mannering si. Nat Commun. 2021 Aug 25;12(1):5110. doi: 10.1038/s41467-021-25404-x. Nat Commun. 2021. PMID: 34433824 Free PMC article.
Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.
Tye-Din JA, Stewart JA, Dromey JA, Beissbarth T, van Heel DA, Tatham A, Henderson K, Mannering SI, Gianfrani C, Jewell DP, Hill AV, McCluskey J, Rossjohn J, Anderson RP. Tye-Din JA, et al. Among authors: mannering si. Sci Transl Med. 2010 Jul 21;2(41):41ra51. doi: 10.1126/scitranslmed.3001012. Sci Transl Med. 2010. PMID: 20650871
Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Broughton SE, Petersen J, Theodossis A, Scally SW, Loh KL, Thompson A, van Bergen J, Kooy-Winkelaar Y, Henderson KN, Beddoe T, Tye-Din JA, Mannering SI, Purcell AW, McCluskey J, Anderson RP, Koning F, Reid HH, Rossjohn J. Broughton SE, et al. Among authors: mannering si. Immunity. 2012 Oct 19;37(4):611-21. doi: 10.1016/j.immuni.2012.07.013. Epub 2012 Oct 11. Immunity. 2012. PMID: 23063329 Free article.
Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes.
Pathiraja V, Kuehlich JP, Campbell PD, Krishnamurthy B, Loudovaris T, Coates PT, Brodnicki TC, O'Connell PJ, Kedzierska K, Rodda C, Bergman P, Hill E, Purcell AW, Dudek NL, Thomas HE, Kay TW, Mannering SI. Pathiraja V, et al. Among authors: mannering si. Diabetes. 2015 Jan;64(1):172-82. doi: 10.2337/db14-0858. Epub 2014 Aug 25. Diabetes. 2015. PMID: 25157096
74 results